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A amide compound and its preparation and use (by machine translation)

The invention provides an amide compound and its preparation and use, the amine compound has the following formula I states the acid radical structure shown, it is a new kind of fungicide, can apply to the agriculture, forestry on insect pest of disease, has good control effect, especially for soybean rust, cucumber downy mildew and cucumber powdery mildew has very good control effect, in the amide compound concentration is 100 ppm when, for soybean rust preventive effect in 80% or more; in the amide compound concentration is 400 ppm when the, of cucumber downy mildew control effect in 80% or more, of cucumber powdery mildew control effect in 90% or more. And its preparation method is simple and efficient, easy to large-scale production, the application prospect is extensive. (by machine translation)

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Archives for Chemistry Experiments of Isothiazole

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Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Raubenheimer, Helgard G. and a compound is mentioned, SDS of cas: 288-16-4, Isothiazole, introducing its new discovery. SDS of cas: 288-16-4

Preparation and Characterization of the First Isothiazolyl and Isothiazolinylidene Complexes of Gold(I)

Isothiazolyl complexes have been synthesized by the addition of isothiazol-5-yllithium to gold(I) chloride or tetrahydrothiophene(pentafluorophenyl)gold complexes.Protonation or alkylation of these isothiazolyl complexes yielded the corresponding isothiazolinylidene complexes.The mono(isothiazolyl)-aurate and mono(isothiazolinylidene) complexes undergo homoleptic rearrangement.The molecular structure of the mono(isothiazolyl) complex shows a gold-carbon bond length of 2.032(7) Angstroem.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Extended knowledge of 3,4-Dichloroisothiazole-5-carboxylic acid

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Use of Sulphur-Containing Heteroaromatic Acid Analogues as Bactericides

The present invention relates to the use of compounds according to formula (I) for controlling bacterial harmful organisms in useful plants. Moreover, the present invention relates to a method for controlling bacterial harmful organisms in useful plants by treating them with compounds according to formula (I).

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.Quality Control of Isothiazole, Name is Isothiazole, molecular formula is C3H3NS, Quality Control of Isothiazole. In a Article, authors is An, Yi£¬once mentioned of Quality Control of Isothiazole

Stacking Interactions between 9-Methyladenine and Heterocycles Commonly Found in Pharmaceuticals

Complexes of 9-methyladenine with 46 heterocycles commonly found in drugs were located using dispersion-corrected density functional theory, providing a representative set of 408 unique stacked dimers. The predicted binding enthalpies for each heterocycle span a broad range, highlighting the strong dependence of heterocycle stacking interactions on the relative orientation of the interacting rings. Overall, the presence of NH and carbonyl groups lead to the strongest stacking interactions with 9-methyadenine, and the strength of -stacking interactions is sensitive to the distribution of heteroatoms within the ring as well as the specific tautomer considered. Although molecular dipole moments provide a sound predictor of the strengths and orientations of the 28 monocyclic heterocycles considered, dipole moments for the larger fused heterocycles show very little correlation with the predicted binding enthalpies.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Can You Really Do Chemisty Experiments About 288-16-4

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Application of 288-16-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.288-16-4, Name is Isothiazole, molecular formula is C3H3NS. In a article£¬once mentioned of 288-16-4

Five-Membered Ring Systems: With N and S Atom

This review chapter describes the syntheses and reactions of these 5-membered heterocyclic ring systems containing nitrogen and sulfur (reported during 2018). The importance of these p-rich heterocycles in medicinal chemistry and natural products is also covered.

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

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Application of 288-16-4, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Application of 288-16-4, Name is Isothiazole, molecular formula is C3H3NS. In a Patent, authors is £¬once mentioned of Application of 288-16-4

Amino pyridine derivatives

Novel 4-pyridinamine derivatives having the formula STR1 [where R1 and R2 are aryl or heteroaryl (optionally linked together by a lower alkylene bridge) or one of R1 and R2 is aryl or heteroaryl and the other of R1 and R2 is lower alkyl or ar(lower)alkyl, R3 and R4 are each hydrogen or lower alkyl and n is 0 or 1] and their non-toxic acid addition salts are described. They show CNS activity and may be used as antidepressant drugs. Some also show stimulant activity. Novel intermediates having the formula STR2 are also described.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Final Thoughts on Chemistry for Isothiazole

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: Isothiazole, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 288-16-4, Name is Isothiazole, molecular formula is C3H3NS

Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors

Cytochrome P450 17A1 (CYP17A1) is an important target in the treatment of prostate cancer because it produces androgens required for tumour growth. The FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal scaffold similar to the endogenous CYP17A1 substrates. Abiraterone is structurally similar to the substrates of other cytochrome P450 enzymes involved in steroidogenesis, and interference can pose a liability in terms of side effects. Using non-steroidal scaffolds is expected to enable the design of compounds that interact more selectively with CYP17A1. Therefore, we combined a structure-based virtual screening approach with density functional theory (DFT) calculations to suggest non-steroidal compounds selective for CYP17A1. In vitro assays demonstrated that two such compounds selectively inhibited CYP17A1 17alpha-hydroxylase and 17,20-lyase activities with IC50 values in the nanomolar range, without affinity for the major drug-metabolizing CYP2D6 and CYP3A4 enzymes and CYP21A2, with the latter result confirmed in human H295R cells.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

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Related Products of 18480-53-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.18480-53-0, Name is 3,4-Dichloroisothiazole-5-carboxylic acid, molecular formula is C4HCl2NO2S. In a Patent£¬once mentioned of 18480-53-0

Isothiazolecarboxylic acid derivatives, rice blast control agents containing the same as active ingredients, and rice blast control method applying the control agents

Application of a rice blast control agent containing an isothiazolecarboxylic acid derivative of the below-described formula, which shows excellent activity against rice blast (Pyricularia oryzae) in rice cultivation, to the water surface of a paddy rice field results in the absorption of the derivative through roots of rice plants, so that the resistance of the rice plants can be enhanced. STR1 wherein R1 and R2 independently mean a hydrogen or halogen atom or a particular group, and Y stands for an OR3 group (R3 being a hydrogen or alkali metal atom or a particular group), an NHR4 group (R4 being a hydrogen atom or a particular group), or a morpholino group.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

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Progress toward the total synthesis of callipeltin A (I): Asymmetric synthesis of (3S,4R)-3,4-dimethylglutamine

(equation presented) During the total synthesis of the novel cyclic depsipeptide callipeltin A (1), the unit (3S,4R)-3,4-dimethylglutamine, was successfully synthesized by asymmetric Michael addition and subsequent electrophilic azidation. The key feature of this approach is the generation of three adjacent stereogenic centers using the same camphorsultam chiral auxiliary.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Discovery of 822-82-2

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Reference of 822-82-2, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.822-82-2, Name is Isothiazole-4-carboxylic acid, molecular formula is C4H3NO2S. In a article£¬once mentioned of 822-82-2

Substituted phenyl compounds

STR1Compounds of formula (I) are described wherein R 1 is hydrogen, -(lower alkyl) q (CO 2 R 6 or OH), –CN, –C(R 7) NOR 8, NO 2, –O(lower alkyl)R 9, –C C–R 10, –CR 11 C(R 12)(R 13), –C( O)CH 2 C( O)CO 2 H, –CO(R 14), alkylthio, alkylsulphinyl, alkylsulphonyl, carbamoyl, thiocarbamoyl, substituted carbamoyl, substituted thiocarbamoyl, sulphamoyl or an optionally substituted nitrogen-containing ring, m, n, o and p are independently zero or 1 and R 2, R 3, R 4 and R 5 are various groups; and physiologically acceptable salts, N-oxides and prodrugs thereof. The compounds have endothelin antagonist activity and are useful as pharmaceuticals.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com