Category: 27148-03-4

27148-03-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 27148-03-4, molecular formula is C7H5NO2S2, introducing its new discovery.

3-phenylpropionic acid derivatives

The invention relates to new compounds, 3-phenylpropionic acid derivatives of formula (I) wherein W represents COOH group or its bioisosters, or -COO-C1-C4-alkyl group; Y represents NH, N-C1-C10-alkyl, O, or S; X represents O, S, NH, N-C1-C10-alkyl, N-aryl, NSO2-C1-C10-alkyl, N-SO2-aryl, or N-SO2-heteroaryl; R1 to R8 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicament

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.27148-03-4, you can also check out more blogs about27148-03-4

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, molecular formula is C7H5NO2S2, 27148-03-4. In a Article, authors is Tarulli, Susana H.£¬once mentioned of 27148-03-4

Structural and Spectroscopic Characterization of Two New Thallium(I)/Thiosaccharinate Complexes

The crystal structures of [Tl(tsac)] (1) and [Tl(tsac)-(ophen)] (2) (tsac = anion of thiosaccharin; ophen = 1,10 phenanthroline) have been determined at 116 K by single crystal X-ray diffractometry. Complex 1 crystallizes in the monoclinic space group P21/a with Z = 4 and complex 2 in the monoclinic space group C2/c with Z = 8.In both complexes TI is coordinated to a thiosaccharinate anion through its sulphur and nitrogen atoms. A distorted eight fold coordination sphere around the cation in complex 1 is completed with two other longer Tl-S bonds and four Tl…O contacts with five symmetry related neighbouring thiosaccharinate anions. A phenanthroline molecule acting as a bidentate ligand through its nitrogen atoms completes a four-fold coordination around the metal atom in complex 2. The infrared spectra of both complexes were also recorded and their most important features discussed on the basis of its structural peculiarities.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. 27148-03-4, In my other articles, you can also check out more blogs about 27148-03-4

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27148-03-4, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, molecular formula is C7H5NO2S2. In a Article, authors is Pinky, Tamanna£¬once mentioned of 27148-03-4

Activation of thiosaccharin at a polynuclear osmium cluster

The reaction of thiosaccharin (tsacH) with the triosmium cluster [Os3(CO)10(NCMe)2] furnishes the decacarbonyl isomers [HOs3(CO)10(mu-S-tsac)] (1) and [HOs3(CO)10(mu-N,S-1,3-tsac)] (2) in a 3:1 ratio at room temperature. These isomers differ by the coordination mode displayed by tsac ligand. The tsac moiety functions as an edge-bridging ligand via the sulfur atom in 1 while in 2 the bridging of adjacent osmium centers is achieved through the sulfur and nitrogen groups. The ancillary hydride in both products shares the Os?Os edge that is bridged by the heterocyclic ligand. Heating 1 at 80 C affords 2 and demonstrates that the former cluster is the product of kinetic control. The conversion of 1 ? 2 has been investigated by DFT and the isomerization pathway elucidated. The DFT calculations confirm cluster 2 as the thermodynamically preferred isomer in this pair of products. Thermolysis of 2 in refluxing toluene affords the hexanuclear cluster [H2Os6(CO)17(mu-C,N-1,2-C6H4CNSO2)2(mu3-S)(mu4-S)] (3) via carbon-sulfur bond scission and subsequent capture of the extruded sulfur by the cluster core. The molecular structures for the three new clusters have been determined by single-crystal X-ray diffraction analyses.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.27148-03-4. In my other articles, you can also check out more blogs about 27148-03-4

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27148-03-4, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, molecular formula is C7H5NO2S2. In a Article, authors is Nabar£¬once mentioned of 27148-03-4

Synthesis of 1,2,3-Benzothiadiazine-1,1 -dioxide Derivatives and their Pharmacological Properties

Formation of 4-(Sub)-amino-1,2,3-benzothiadiazine-1,1-dioxide was established by earlier reported base catalysed ring expansion reaction. Products thus obtained, were stable in aqueous alkaline and acidic medium and on alkylation/acylation furnished 4-amino derivative (4, 5) exclusively, instead of 2-N-derivative (3). Preliminary pharmacological screening was done and the results were positive.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 27148-03-4, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 27148-03-4, in my other articles.

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27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, belongs to isothiazole compound, is a common compound. 27148-03-4In an article, authors is Al-Jibori, Subhi A., once mentioned the new application about 27148-03-4.

Palladium(II) benzisothiazolinate (bit) complexes with amino-, acetylamino-, heterocyclic and phosphine co-ligands. Crystal structure of [Pd(bit)2(kappa2-dppe)]¡¤2EtOH

Abstract A series of square-planar palladium(II) benzisothiazolinate (bit) of the general type [Pd(bit)2L2] have been prepared and characterized by analytical and spectroscopic methods. Two synthetic routes have been employed, namely reactions of [Pd(bit)2]¡¤H2O with two equivalents of ligands (L = amine, amide, phosphine) or nucleophile displacement of chloride by benzisothiazolinate starting from trans-[PdCl2L2]. Both routes afford the new complexes in good yields as easily isolated, air and moisture stable, colored solids. The precursor, [Pd(bit)2]¡¤H2O, is itself prepared in high yields upon reaction of Na[bit] with Na2[PdCl4] in methanol and the analogous platinum complex, [Pt(bit)2]¡¤H2O, is similarly prepared from K2[PtCl4]. It is not clear if these species are mono- or dimeric, and formulation as [M2(mu-bit)4(H2O)2] with the four benzisothiazolinate spanning the metal-metal vector and possibly binding through coordination of nitrogen and oxygen is suggested. Diphosphine adducts, cis-[Pd(bit)2{kappa2-Ph2P(CH2)nPPh2}] (n = 1-4) can be prepared both upon addition of the diphosphine to [Pd(bit)2]¡¤H2O and from reactions of cis-[PdCl2{kappa2-Ph2P(CH2)nPPh2}] with two equivalents of Na[bit]. A crystal structure of cis-[Pd(bit)2(kappa2-dppe)] reveals that the benzisothiazolinate ligands are bonded in a monodentate fashion through nitrogen and this binding mode is proposed for all [Pd(bit)2L2] and [Pd(bit)2L] complexes. With dppb (n = 4) a second product is seen by NMR spectroscopy being proposed to be the part-substituted complex cis-[PdCl(bit)(kappa2-dppb)], while with dppm (n = 1) two further products are seen spectroscopically, proposed as trans-[Pd(bit)2(kappa1-dppm)2] and (more tenuously) [Pd2(bit)4(dppm)2]. The former is also prepared in good yields from reaction of [Pd(kappa2-dppm)2]Cl2 with Na[bit]. These studies show that palladium benzisothiazolinate are easily accessed and show good air and moisture stability.

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An article , which mentions 27148-03-4, molecular formula is C7H5NO2S2. The compound – Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide played an important role in people’s production and life., 27148-03-4

Synthesis and spectroscopic characterization of two new thiosaccharinate salts. Molecular structure of bis(triphenylphosphine)iminium thiosaccharinate, PNP(tsac)

We report the synthesis, FTIR, Raman and NMR spectroscopic features of bis(triphenylphosphine)iminium and tetrabutylammonium thiosaccharinates, PNP(tsac) and NBu 4 (tsac) (tsac: thiosaccharinate anion, PNP: bis(triphenylphosphine)iminium). The molecular structure of the former compound was determined by X-ray diffraction methods. The salt crystallizes in the monoclinic P21/n space group with a = 9.6481(9), b = 29.258(3), c = 13.177(2)?A, beta = 97.53(1), and Z = 4 molecules per unit cell. Slight but significant changes in the bonding structure of the thiosaccharinate anion as compared with those reported for the neutral molecule are observed. Springer-Verlag 2007.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! Read on for other articles about 1273-94-5!, 27148-03-4

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27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, belongs to isothiazole compound, is a common compound. 27148-03-4In an article, authors is Al-Jibori, Subhi A., once mentioned the new application about 27148-03-4.

Combining anti-cancer drugs with artificial sweeteners: Synthesis and anti-cancer activity of saccharinate (sac) and thiosaccharinate (tsac) complexes cis-[Pt(sac)2(NH3)2] and cis-[Pt(tsac)2(NH3)2]

The new platinum(II) complexes cis-[Pt(sac)2(NH3)2] (sac = saccharinate) and cis-[Pt(tsac)2(NH3)2] (tsac = thiosaccharinate) have been prepared, the X-ray crystal structure of cis-[Pt(sac)2(NH3)2].H2O reveals that both saccharinate anions are N-bound in a cis-arrangement being inequivalent in both the solid-state and in solution at room temperature. Preliminary anti-cancer activity has been assessed against A549 human alveolar type-II like cell lines with the thiosaccharinate complex showing good activity.

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27148-03-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, cas is 27148-03-4,the isothiazole compound, it is a common compound, a new synthetic route is introduced below.

General procedure: The [Zn(tsac)2(o-phen)] complex was prepared by addition of a dissolution of Zn(NO3)26H2O (14.85 mg, 0.049 mmol, 2 ml) into a thiosaccharine solution (20 mg, 0.1 mmol/ethanol:water 1:1,2 ml). A o-phenantroline solution was finally added drop by drop (ethanol:water 1:1, 2 ml) and a yellow power was obtained. The resulting yellow solid was filtered and washed with cold water. Crystals suitable for X-ray diffraction studies were produced by slow diffusion of diethyl ether to the mother solution. Yield: 74%

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, 27148-03-4

Reference£º
Article; Delgado, Fermin; Freire, Eleonora; Baggio, Ricardo; Gonzalez Pardo, Veronica; Dorn, Viviana; Dennehy, Mariana; Inorganica Chimica Acta; vol. 479; (2018); p. 266 – 274;,
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Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, as a common heterocyclic compound, it belongs to isothiazole compound, and cas is 27148-03-4, its synthesis route is as follows.,27148-03-4

Room temperature: To a benzene solution (20mL) containing [Os3(CO)10(NCMe)2] (0.13g, 0.14mmol) was added tsacH (56g, 0.28mmol), after which the solution was allowed to stir at room temperature for 2h. TLC examination of the reaction revealed the presence of two new products in a 3:1 ratio representing 1 and 2, respectively. The products were isolated by chromatography using an eluent composed of cyclohexane/ CH2Cl2 (1:1, v/v) that afforded two bands corresponding to [HOs3(CO)10(mu-N,S-1,3-tsac)] (2) (32mg, 22%) and [HOs3(CO)10(mu-S-tsac)] (1) (0.10g, 68%) in order of elution. Each product was obtained as orange crystals after recrystallization from n-hexane/CH2Cl2 at 4C. Data for 1: Anal. Calc. for C17H5NO12Os3S2: C, 19.44; H, 0.48, N, 1.33. Found: C, 19.92; H, 0.54, N, 1.36%. IR (nuCO, CH2Cl2): 211m, 2076vs, 2066s, 2028s, 2019s, 1992m cm-1. 1H NMR (CDCl3): delta 8.00 (m, 1H), 7.90 (m, 1H), 7.86 (m, 2H),-17.10 (s, 1H). Data for 2: Anal. Calc. for C17H5NO12Os3S2: C, 19.44; H, 0.48, N, 1.33. Found: C, 19.98; H, 0.52; N, 1.37%. IR (nuCO, CH2Cl2): 2113m, 2076s, 2065s, 2029s, 2018s, 1994w, 1982w cm-1. 1H NMR (CDCl3): delta 7.94 (d, J 7.2Hz, 1H), 7.84 (d, J 7.2Hz, 1H), 7.72 (m, 2H),-13.96 (s, 1H).

With the complex challenges of chemical substances, we look forward to future research findings about Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide

Reference£º
Article; Pinky, Tamanna; Rahman, Md Matiar; Ghosh, Shishir; Azam, Kazi A.; Mia, Md. Jadu; Alam, Md. Mahbub; Tocher, Derek A.; Richmond, Michael G.; Kabir, Shariff E.; Journal of Organometallic Chemistry; vol. 880; (2019); p. 223 – 231;,
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As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO317,mainly used in chemical industry, its synthesis route is as follows.,27148-03-4

A solution of thiosaccharin (tsacH) (0.04 g, 0.24 mmol) in methanol (8 cm3) was added to a solution of K2[PtCl4] (0.05 g, 0.12 mmol) in water (3 cm3). The orange mixture was heated at reflux on a steam bath for 2 h. After cooling to room temperature the brown solid formed was filtered off, washed with water and dried in a vacuum oven to give 1 (0.049 g, 70%). 1H NMR (d6-dmso): delta 8.50 (d, J 7.0 Hz, 2H), 8.86 (d, J 6.8 Hz, 2H), 7.76 (m, 4H); IR v/cm-1; IR(KBr) 3085w, 1419s, 1340vs, 1100vs, 1012s, 804vs, 366m cm-1; Elemental Anal. Calc. for PtS4N2O4C14H8¡¤H2O. Found: C, 27.58 (27.63); H, 1.64 (1.49); N, 4.60 (4.59)%.

With the synthetic route has been constantly updated, we look forward to future research findings about Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide,belong isothiazole compound

Reference£º
Article; Al-Jibori, Subhi A.; Al-Jibori, Mohamed H.S.; Hogarth, Graeme; Inorganica Chimica Acta; vol. 398; (2013); p. 117 – 123;,
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