Category: 99-04-7

An article Ring-Opening Ortho-C-H Allylation of Benzoic Acids with Vinylcyclopropanes: Merging Catalytic C-H and C-C Activation Concepts WOS:000485089300038 published article about CARBOXYLIC-ACIDS; BOND FUNCTIONALIZATION; HYDROARYLATION; ARYLATION; ALKYNES; CYCLOPROPENES; ROUTES; ARENES; SP(2) in [Hu, Zhiyong; Hu, Xiao-Qiang; Zhang, Guodong; Goossben, Lukas J.] Ruhr Univ Bochum, Lehrstuhl Organ Chem 1, Univ Str 150, D-44801 Bochum, Germany in 2019, Cited 65. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. SDS of cas: 99-04-7

A Ru-catalyzed selective and atom-economic ortho-C-H allylation of aromatic acids with vinylcyclopropanes is reported. The reaction proceeds with selective cleavage of both a C-H and a C-C bond. A wide range of allylarenes were synthesized in high yields and stereoselectivities. The vinylcyclopropane substrates can optionally be generated in situ from a diazo compound and 1,3-butadiene. Concise syntheses of isocoumarin and 3,4-dihydroisocoumarin derivatives underline the synthetic utility of the reaction.

SDS of cas: 99-04-7. Welcome to talk about 99-04-7, If you have any questions, you can contact Hu, ZY; Hu, XQ; Zhang, GD; Goossben, LJ or send Email.

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An article Practical and rapid construction of 2-pyridyl ketone library in continuous flow WOS:000588040300001 published article about ASYMMETRIC HYDROGENATION; NITRIC-ACID; CHEMISTRY; SYSTEM; GENERATION; CONVERSION; NITRATION; ARYL in [Sun, Maolin; Li, Jianchang; Liang, Chaoming; Shan, Chao; Shen, Xinyuan; Ma, Yueyue; Ye, Jinxing] East China Univ Sci & Technol, Minist Educ, Sch Pharm, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China; [Cheng, Ruihua] East China Univ Sci & Technol, Sch Chem Engn, Shanghai 200237, Peoples R China in 2021, Cited 59. Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

2-Pyridyl ketones widely appear in bioactive molecules, natural products, and are employed as precursors of chiral 2-pyridine alky/aryl alcohols or 2-aminoalkyl pyridine ligands for asymmetric catalysis. Herein, a practical method for the rapid synthesis of 2-pyridyl ketone library in continuous flow is reported, in which the 2-lithiopyridine formed by Br/Li exchange reacts with commercially available esters to obtain 2-pyridyl ketones in a good yield at short reaction time. This protocol functions broadly on a variety of esters and has been applied to the synthesis of TGF-beta type 1 receptor inhibitor LY580276 intermediate in an environmentally friendly method. It is rapid, reliable, and cost-efficient to afford diverse kinds of 2-pyridyl ketones in the compound library.

Formula: C8H8O2. Welcome to talk about 99-04-7, If you have any questions, you can contact Sun, ML; Li, JC; Liang, CM; Shan, C; Shen, XY; Cheng, RH; Ma, YY; Ye, JX or send Email.

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Authors Hang, W; Yi, YP; Xi, CJ in AMER CHEMICAL SOC published article about PALLADIUM-CATALYZED CARBOXYLATION; GRIGNARD-REAGENTS; BENZYL CHLORIDES; HALIDES; TRANSFORMATION; COMPLEXES; INSERTION; ALKENES; ESTERS in [Hang, Wei; Yi, Yaping; Xi, Chanjuan] Tsinghua Univ, Dept Chem, MOE Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China; [Xi, Chanjuan] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China in 2020, Cited 56. Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Cp2TiCl2-catalyzed carboxylation of aryl chlorides with carbon dioxide to afford benzoic acids in good yields has been achieved in the presence of n-BuMgCl. The reaction proceeds by a sequential magnesium halide exchange reaction and carboxylation with CO2 in a wide variety of aryl chlorides under mild conditions.

Formula: C8H8O2. Welcome to talk about 99-04-7, If you have any questions, you can contact Hang, W; Yi, YP; Xi, CJ or send Email.

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Huy, PH; Mbouhom, C in [Huy, Peter H.; Mbouhom, Christelle] Saarland Univ, Inst Organ Chem, POB 151150, D-66041 Saarbrucken, Germany published Formamide catalyzed activation of carboxylic acids – versatile and cost-efficient amidation and esterification in 2019.0, Cited 84.0. Safety of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

A novel, broadly applicable method for amide C-N and ester C-O bond formation is presented based on formylpyrrolidine (FPyr) as a Lewis base catalyst. Herein, trichlorotriazine (TCT), which is the most cost-efficient reagent for OH-group activation, was employed in amounts of <= 40 mol% with respect to the starting material (100 mol%). The new approach is distinguished by excellent cost-efficiency, waste-balance (E-factor down to 3) and scalability (up to >80 g). Moreover, high levels of functional group compatibility, which includes acid-labile acetals and silyl ethers, are demonstrated and even peptide C-N bonds can be formed. In comparison to reported amidation procedures using TCT, yields are considerably improved (for instance from 26 to 91%) and esterification is facilitated for the first time in synthetically useful yields. These significant enhancements are rationalized by activation by means of acid chlorides instead of less electrophilic acid anhydride intermediates.

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Authors Song, XJ; Wang, XM; Sun, Q; Huang, ST; Wang, Y in CHINESE JOURNAL STRUCTURAL CHEMISTRY published article about FACILE SYNTHESIS; DERIVATIVES; 1,3,4-THIADIAZOLE; ANTICANCER in [Song Xin-Jian; Huang Sheng-Tian] Sichuan Univ Sci & Engn, Coll Chem & Environm Engn, Zigong 643000, Peoples R China; [Song Xin-Jian; Wang Xu-Mei; Sun Qi; Wang Yan] Hubei Univ Nationalities, Sch Chem & Environm Engn, Enshi 445000, Peoples R China in 2019, Cited 17. SDS of cas: 99-04-7. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

N-(5-Aryl-1,3,4-thiadiazol-2-yl)-N’-((E)-styryl)ureas 4a similar to 4i were designed and synthesized as antitumor agents, and their structures were characterized by IR, H-1 NMR, C-13 NMR, MS and elemental analysis. The single crystal of compound 4a, C17H13FN4OS, was also determined by X-ray crystallography. Crystal data: monoclinic, space group P21/n, a = 4.9401(8), b = 8.7100(15), c = 36.604(6) angstrom, beta = 93.320(3)degrees, V = 1572.4(5) angstrom(3), Z = 4, F(000) = 704, D-c = 1.438 g/cm(3), mu = 0.228 mm(-1), R = 0.0600 and wR = 0.1448 for 2743 independent reflections (R-int = 0.0418) and 2174 observed ones (I > 2 sigma(I)). The in vitro antitumor activities of compounds 4a similar to 4i were preliminarily evaluated by the standard MTT assay.

Welcome to talk about 99-04-7, If you have any questions, you can contact Song, XJ; Wang, XM; Sun, Q; Huang, ST; Wang, Y or send Email.. SDS of cas: 99-04-7

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Zhang, QH; He, HH; Wang, HB; Zhang, Z; Chen, C in [Zhang, Qiaohong; He, Honghao; Wang, Huibin; Chen, Chen] Ningbo Univ, Sch Mat Sci & Chem Engn, 818 Fenghua Rd, Ningbo 315211, Peoples R China; [Zhang, Zhan] China Tobacco Henan Ind Co Ltd, 8 3rd Ave, Zhengzhou 450001, Peoples R China published Efficient catalytic oxidation of methyl aromatic hydrocarbon with N-alkyl pyridinium salts in 2019, Cited 47. Recommanded Product: 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

A series of N-alkyl pyridinium salts were synthesized and employed as metal-free catalyst for the selective oxidation of methyl aromatic hydrocarbon with molecular oxygen. The electronic effect of the substitutes was found to be an important factor for the catalytic performance. With the introduction of electron-donating substitute -N(CH3)(2), the conversion of p-xylene and selectivity of p-toluic acid could be simultaneously increased. 1-Benzyl-4-N,N-dimethylaminopyridinium salt showed the highest catalytic activity, and 95% conversion with 84% of selectivity to p-toluic acid could be obtained for the selective oxidation of p-xylene. Several methyl aromatic hydrocarbons could all be efficiently oxidized with the reported catalyst at the absence of any metal species.

Welcome to talk about 99-04-7, If you have any questions, you can contact Zhang, QH; He, HH; Wang, HB; Zhang, Z; Chen, C or send Email.. Recommanded Product: 3-Methylbenzoic acid

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Isothiazole – Wikipedia,
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An article Copper-Catalyzed Enantioselective Allylic Alkylation with a gamma-Butyrolactone-Derived Silyl Ketene Acetal WOS:000502594800001 published article about ASYMMETRIC-SYNTHESIS; CONJUGATE ADDITION; ALDOL ADDITIONS; COMPLEXES; LACTONES; REGIOSELECTIVITY; SUBSTITUTION; MECHANISM; BOND in [Jette, Carina, I; Stoltz, Brian M.] CALTECH, Warren & Katharine Schlinger Lab Chem & Chem Engn, Pasadena, CA 91125 USA; [Tong, Z. Jaron; Hadt, Ryan G.] CALTECH, Arthur Amos Noyes Lab Chem Phys, Pasadena, CA 91125 USA in 2020, Cited 45. Product Details of 99-04-7. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Herein, we report a Cu-catalyzed enantioselective allylic alkylation using a gamma-butyrolactone-derived silyl ketene acetal. Critical to the development of this work was the identification of a novel mono-picolinamide ligand with the appropriate steric and electronic properties to afford the desired products in high yield (up to 96 %) and high ee (up to 95 %). Aryl, aliphatic, and unsubstituted allylic chlorides bearing a broad range of functionality are well-tolerated. Spectroscopic studies reveal that a Cu-I species is likely the active catalyst, and DFT calculations suggest ligand sterics play an important role in determining Cu coordination and thus catalyst geometry.

Welcome to talk about 99-04-7, If you have any questions, you can contact Jette, CI; Tong, ZJ; Hadt, RG; Stoltz, BM or send Email.. Product Details of 99-04-7

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Computed Properties of C8H8O2. Authors Chen, C; Wang, ZQ; Gong, YY; Wang, JC; Yuan, Y; Cheng, H; Sang, W; Chaemchuen, S; Verpoort, F in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Chen, Cheng; Wang, Zhi-Qin; Wang, Ji-Chao; Yuan, Ye; Sang, Wei; Chaemchuen, Somboon; Verpoort, Francis] Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, 122 Luoshi Rd, Wuhan 430070, Peoples R China; [Gong, Yan-Yan] Qilu Univ Technol, Shandong Acad Sci, State Key Lab Biobased Mat & Green Papermaking, Jinan, Peoples R China; [Cheng, Hua] Hubei Univ Arts & Sci, Dept Chem Engn & Food Sci, Xiangyang 441053, Peoples R China; [Chaemchuen, Somboon; Verpoort, Francis] Natl Res Tomsk Polytech Univ, Lenin Ave 30, Tomsk 634050, Russia; [Verpoort, Francis] Univ Ghent, Global Campus,119 Songdomunhwa Ro, Incheon 406840, South Korea in 2021, Cited 81. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Herein, cobalt embedded in nitrogen-doped porous carbon (Co@NC) was developed as a robust heterogeneous catalyst for the dehydrogenative coupling of primary alcohols and hydroxides. With Co@NC as the first earth-abundant metal/carbon composite material for this transformation, numerous aromatic and aliphatic carboxylic acids were efficiently afforded. Notably, the newly prepared Co@NC was fabricated in a facile and straightforward manner and reused up to 15 recycle rounds without activity decay. It is also worth emphasizing that the catalyst recycling was realized via magnetic separation with no special treatment or activation. Additionally, further experiments elucidated the pivotal role of the cobalt and nitrogen elements dispersed in the carbon matrix as well as the hierarchical porosity (micro-/mesopores) in the catalytic activity and recyclability. Considering the active sites of Co@NC, we envisioned that the Co-N species was the most active site, while other active sites such as Co-O, Co-0 species and free N-doped carbon were also present, but demonstrating lower activity or stability in comparison with the Co-N species. Additional mechanistic investigations were carried out to gain more insights into the possible reaction pathways. We found that the aldehyde was identified as a crucial intermediate, and two possible pathways were proposed for this catalytic process. (C) 2020 Elsevier Ltd. All rights reserved.

Computed Properties of C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

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An article Multi-purpose heterogeneous catalyst material from an amorphous cobalt metal-organic framework WOS:000654939600001 published article about SINGLE-ATOM CATALYSTS; N-C CATALYST; OXYGEN REDUCTION; SELECTIVE OXIDATION; CARBON CATALYSTS; ELECTROCATALYSTS; HALIDES in [Ping, Kefeng; Alam, Mahboob; Kahnert, Sean Ray; Bhadoria, Rohit; Jarving, Ivar; Starkov, Pavel] Tallinn Univ Technol, Dept Chem & Biotechnol, Tallinn 12618, Estonia; [Mere, Arvo; Mikli, Valdek] Tallinn Univ Technol, Dept Mat & Environm Technol, Tallinn 19086, Estonia; [Kaarik, Maike; Leis, Jaan; Kongi, Nadezda] Univ Tartu, Inst Chem, EE-50411 Tartu, Estonia; [Aruvali, Jaan; Paiste, Paarn] Univ Tartu, Inst Ecol & Earth Sci, EE-50411 Tartu, Estonia; [Kikas, Arvo; Kisand, Vambola] Univ Tartu, Inst Phys, EE-50411 Tartu, Estonia in 2021, Cited 51. Application In Synthesis of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Sustainable technologies rely on the development of universal catalyst materials. While a lot of the attention has been given to improving the performance of one single catalyst material for one specific application, there is still a need to find ways to develop catalysts that can simultaneously be utilized for several chemo- and electrocatalytic processes. In this work, we have surveyed a series of novel, cobalt-based catalyst materials derived from an amorphous MOF in an array of diverged applications. Specifically, we have focused on organic transformations such as oxidative of alkylarenes and benzylic homocoupling reactions as well as several electrocatalytic processes, which directly relate to energy conversion and storage devices, such as oxygen reduction (ORR), oxygen evolution (OER) and hydrogen evolution (HER) reactions. We have observed that only one material, TAL-2-900, delivered the optimal solution. The stability and recyclability of this unique multifunctional material has been examined.

Welcome to talk about 99-04-7, If you have any questions, you can contact Ping, KF; Alam, M; Kahnert, SR; Bhadoria, R; Mere, A; Mikli, V; Kaarik, M; Aruvali, J; Paiste, P; Kikas, A; Kisand, V; Jarving, I; Leis, J; Kongi, N; Starkov, P or send Email.. Application In Synthesis of 3-Methylbenzoic acid

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Formula: C8H8O2. Authors Marrazzini, G; Giovannini, T; Egidi, F; Cappelli, C in AMER CHEMICAL SOC published article about in [Marrazzini, Gioia; Egidi, Franco; Cappelli, Chiara] Scuola Normale Super Pisa, I-56126 Pisa, Italy; [Giovannini, Tommaso] Norwegian Univ Sci & Technol, Dept Chem, N-7491 Trondheim, Norway in 2020, Cited 94. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

We present a computational study of polarizabilities and hyperpolarizabilities of organic molecules in aqueous solutions, focusing on solute-water interactions and the way they affect a molecule’s linear and non-linear electric response properties. We employ a polarizable quantum mechanics/molecular mechanics (QM/MM) computational model that treats the solute at the QM level while the solvent is treated classically using a force field that includes polarizable charges and dipoles, which dynamically respond to the solute’s quantum-mechanical electron density. Quantum confinement effects are also treated by means of a recently implemented method that endows solvent molecules with a parametric electron density, which exerts Pauli repulsion forces upon the solute. By applying the method to a set of aromatic molecules in solution we show that, for both polarizabilities and first hyperpolarizabilities, observed solution values are the result of a delicate balance between electrostatics, hydrogen-bonding, and non-electrostatic solute solvent interactions.

Formula: C8H8O2. Welcome to talk about 99-04-7, If you have any questions, you can contact Marrazzini, G; Giovannini, T; Egidi, F; Cappelli, C or send Email.

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