Category: 99-04-7

An article Functionalized Allyl Aryl Ether Synthesis from Benzoic Acids Using a Dearomatization and Decarboxylative Allylation Approach WOS:000456632800018 published article about RADICAL CYCLIZATION; RAPID ACCESS; ETHERIFICATION; REARRANGEMENT; CONSTITUENTS; DERIVATIVES; GENERATION; PHENOL in [Hsieh, Cheng-En; Jiang, Yu-Min; Chou, Chih-Ming] Natl Univ Kaohsiung, Dept Appl Chem, 700 Kaohsiung Univ Rd, Kaohsiung 81148, Taiwan in 2019.0, Cited 55.0. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Formula: C8H8O2

A strategy toward the preparation of substituted allyl aryl ethers from benzoic acids via a dearomatization and decarboxylative allylation (DcA) reaction is presented. The benzoic acids undergo a dearomatization to give alkylated 2,5-cyclohexadienyl ketoesters which are subjected to a palladium-catalyzed DcA reaction, providing a variety of functionalized allyl aryl ethers. In addition, the combination of a resonance stabilized DcA reaction with a Claisen rearrangement for the synthesis of multisubstituted phenols and applying to dihydroplicatin B derivative synthesis is also presented.

Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Hsieh, CE; Jiang, YM; Chou, CM or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Li, ZH; Liu, L; Xu, KQ; Huang, TZ; Li, XY; Song, B; Chen, TQ in [Li, Zhaohui; Liu, Long; Xu, Kaiqiang; Huang, Tianzeng; Li, Xinyi; Song, Bin; Chen, Tieqiao] Hainan Univ, Hainan Prov Fine Chem Engn Res Ctr, Hainan Prov Key Lab Fine Chem, Key Lab,Minist Educ Adv Mat Trop Isl Resources, Haikou 570228, Hainan, Peoples R China published Palladium-Catalyzed N-Acylation of Tertiary Amines by Carboxylic Acids: A Method for the Synthesis of Amides in 2020, Cited 54. Name: 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

A palladium-catalyzed N-acylation of tertiary amines by carboxylic acids was achieved through C-N cleavage. This reaction showed a wide substrate scope. Both aromatic and aliphatic acids served well as the acylating reagents and coupled with tertiary amines to produce the corresponding amides in good to excellent yields. With the strategy, bioactive carboxylic acids were also efficiently modified, highlighting the synthetic value of the process in organic synthesis.

Name: 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Li, ZH; Liu, L; Xu, KQ; Huang, TZ; Li, XY; Song, B; Chen, TQ or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Quality Control of 3-Methylbenzoic acid. Authors Siddiki, SMAH; Rashed, MN; Touchy, AS; Jamil, MAR; Jing, Y; Toyao, T; Maeno, Z; Shimizu, K in ROYAL SOC CHEMISTRY published article about in [Siddiki, S. M. A. Hakim; Rashed, Md. Nurnobi; Touchy, Abeda Sultana; Jamil, Md. A. R.; Jing, Yuan; Toyao, Takashi; Maeno, Zen; Shimizu, Ken-ichi] Hokkaido Univ, Inst Catalysis, N-21,W-10, Sapporo, Hokkaido 0010021, Japan; [Toyao, Takashi; Shimizu, Ken-ichi] Kyoto Univ, Elements Strategy Initiat Catalysts & Batteries, Kyoto 6158520, Japan in 2021, Cited 77. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Hydrolysis of amides to carboxylic acids is an industrially important reaction but is challenging due to the difficulty of cleaving the resonance stabilized amidic C-N bond. Twenty-three heterogeneous and homogenous catalysts were examined in the hydrolysis of acetamide. Results showed that Nb2O5 was the most effective heterogeneous catalyst with the greatest yield of acetic acid. A series of Nb2O5 catalysts calcined at various temperatures were characterized and tested in the hydrolysis of acetamide to determine the effects of crystal phase and surface properties of Nb2O5 on catalytic performance. The high catalytic performance observed was attributed mainly to the facile activation of the carbonyl bond by Lewis acid sites that function even in the presence of basic inhibitors (NH3 and H2O). The catalytic studies showed the synthetic advantages of the present method, such as simple operation, catalyst recyclability, additive free, solvent free, and wide substrate scope (>40 examples; up to 95% isolated yield).

About 3-Methylbenzoic acid, If you have any questions, you can contact Siddiki, SMAH; Rashed, MN; Touchy, AS; Jamil, MAR; Jing, Y; Toyao, T; Maeno, Z; Shimizu, K or concate me.. Quality Control of 3-Methylbenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2020 ATMOS CHEM PHYS published article about DICARBOXYLIC-ACIDS; MOLECULAR-DISTRIBUTIONS; BROWN CARBON; ATMOSPHERIC AEROSOLS; PARTICULATE MATTER; PARTICLE EMISSIONS; ALPHA-DICARBONYLS; LIGHT-ABSORPTION; VAPOR-PRESSURES; WILDLAND FUELS in [Sengupta, Deep; Samburova, Vera; Bhattarai, Chiranjivi; Watts, Adam C.; Moosmueller, Hans; Khlystov, Andrey Y.] Desert Res Inst, 2215 Raggio Pkwy, Reno, NV 89512 USA in 2020, Cited 93. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Safety of 3-Methylbenzoic acid

Semivolatile organic compounds (SVOCs) emitted from open biomass burning (BB) can contribute to chemical and physical properties of atmospheric aerosols and also may cause adverse health effects. The polar fraction of SVOCs is a prominent part of BB organic aerosols, and thus it is important to characterize the chemical composition and reactivity of this fraction. In this study, globally and regionally important representative fuels (Alaskan peat, Moscow peat, Pskov peat, eucalyptus, Malaysian peat, and Malaysian agricultural peat) were burned under controlled conditions using the combustion chamber facility at the Desert Research Institute (DRI). Gas- and particle-phase biomass-burning emissions were aged in an oxidation flow reactor (OFR) to mimic 5-7 d of atmospheric aging. Fresh and OFR-aged biomass-burning aerosols were collected on Teflonimpregnated glass fiber filters (TIGF) in tandem with XAD resin media for organic carbon speciation. The polar fraction extracted with dichloromethane and acetone was analyzed with gas chromatography mass spectrometry (GC-MS) for 84 polar organic compounds – including mono- and dicarboxylic acids, methoxylated phenols, aromatic acids, anhydrosugars, resin acids, and sterols. For all these compounds, fuel-based emission factors (EFs) were calculated for fresh and OFR-aged samples. The carbon mass of the quantified polar compounds was found to constitute 5 % to 7 % of the total organic compound mass. A high abundance of methoxyphenols (239 mg kg(-1) for Pskov peat; 22.6 % of total GC-MS characterized mass) and resin acids (118 mg kg(-1) for Alaskan peat; 14.5 % of total GC-MS characterized mass) was found in peat-burning emissions (smoldering combustion). The concentration of some organic compounds (e.g., tetracosanoic acid) with a molecular weight (MW) above 350 g mol(-1) decreased after OFR aging, while abundances of low-MW compounds (e.g., hexanoic acid) increased. This indicated a significant extent of fragmentation reactions in the OFR. Methoxyphenols decreased after OFR aging, while a significant increase (3.7 to 8.6 times) in the abundance of dicarboxylic acids emission factors (EFs), especially maleic acid (10 to 60 times), was observed. EFs for fresh and ratios from fresh-to-aged BB samples reported in this study can be used to perform source apportionment and predict processes occurring during atmospheric transport.

Safety of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Sengupta, D; Samburova, V; Bhattarai, C; Watts, AC; Moosmuller, H; Khlystov, AY or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recently I am researching about CATALYZED DIRECT CARBOXYLATION; CARBON-DIOXIDE; BENZYL CHLORIDES; ELECTROCATALYTIC CARBOXYLATION; RECENT PROGRESS; SILVER CATHODE; ELECTROCARBOXYLATION; REDUCTION; ELECTROSYNTHESIS; PALLADIUM, Saw an article supported by the CNRSCentre National de la Recherche Scientifique (CNRS)European Commission; Ministere de l’Enseignement Superieur et de la RechercheEstonian Research CouncilEuropean Commission; French National Research AgencyFrench National Research Agency (ANR) [ANR-11-LABX-0039]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Bazzi, S; Le Duc, G; Schulz, E; Gosmini, C; Mellah, M. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid. Recommanded Product: 3-Methylbenzoic acid

The reductive carboxylation of aryl halides has been investigated using a samarium electrode as a sacrificial anode to yield the corresponding benzoic acids, providing a smooth strategy for CO2 activation. Carboxylation occurred after an efficient reduction of carbon dioxide mediated by an electrogenerated Sm(ii)-complex acting as a strong monoelectronic reductive reagent.

Recommanded Product: 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Bazzi, S; Le Duc, G; Schulz, E; Gosmini, C; Mellah, M or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Palladium-catalyzed carbonylative synthesis of acylstannanes from aryl iodides and hexamethyldistannane WOS:000575167400014 published article about ACYL; KETONES; CARBOSTANNYLATION; ACYLSTANNYLATION; ALKYNES; SILYL; TIN in [Chen, Bo; Yuan, Yang; Xu, Jian-Xing; Wu, Xiao-Feng] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany; [Franke, Robert] Evonik Ind AG, Paul Baumann Str 1, D-45772 Marl, Germany; [Franke, Robert] Ruhr Univ Bochum, Lehrstuhl Theoret Chem, Univ Str 150, D-44780 Bochum, Germany in 2020, Cited 21. Quality Control of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

In this communication, we describe a new method for the carbonylative synthesis of acylstannanes from aryl iodides and hexamethyldistannane. With Pd(PPh3)(4) as the catalyst and toluene as the solvent at 60 degrees C under 10 bar CO for 16 h, the desired acylstannanes were obtained in good to excellent yields. In order to facilitate isolation and analysis, the obtained acylstannanes were transformed into the corresponding benzoic acids by simply stirring under air for 5 h. (C) 2020 Elsevier B.V. All rights reserved.

Quality Control of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Chen, B; Yuan, Y; Xu, JX; Franke, R; Wu, XF or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recently I am researching about CARBOXYLIC-ACID SALTS; CP-H BONDS; PRIMARY ALCOHOLS; UNACTIVATED C(SP(3))-H; AEROBIC OXIDATION; WATER; AMINES; ESTERIFICATION; ALKYLATION; CONVERSION, Saw an article supported by the DST of India [DST EMR/2015/000285]; UGC, IndiaUniversity Grants Commission, India; Indian Institute of Technology Delhi; DST-FISTDepartment of Science & Technology (India); IIT D. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Dolui, P; Hazra, S; Deb, M; Elias, AJ. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid. HPLC of Formula: C8H8O2

Picolinamide group assisted sp(3) C-H bond oxidation of methylene groups to the corresponding carbonyl compounds has been achieved by using simple bottle ferrocene as catalyst and Cu(OAc)(2) or tert-butyl peroxybenzoate (TBPB) as oxidant under mild conditions. This method is applicable for picolinamide bound organic as well as organometallic compounds with yields in the range of 46-82%. Control experiments and mechanistic studies indicate that a radical mechanism is responsible for these oxidative transformations in which ferrocene acts as a catalyst.

HPLC of Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Dolui, P; Hazra, S; Deb, M; Elias, AJ or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Application In Synthesis of 3-Methylbenzoic acid. In 2019 ORG BIOMOL CHEM published article about ASYMMETRIC REDUCTION; CARBONYL REDUCTASE; DERIVATIVES; CONVERSION; ALCOHOLS in [Wang, Zexu; Li, Zhining; Huang, Zedu; Chen, Fener] Fudan Univ, Dept Chem, Engn Ctr Catalysis & Synth Chiral Mol, 220 Handan Rd, Shanghai 200433, Peoples R China; [Wang, Zexu; Li, Zhining; Huang, Zedu; Chen, Fener] Shanghai Engn Res Ctr Ind Asymmetr Catalysis Chir, 220 Handan Rd, Shanghai 200433, Peoples R China; [Wu, Xiaofan] Fuzhou Univ, Coll Chem Engn, 2 Xueyuan Rd, Fuzhou 350100, Fujian, Peoples R China in 2019, Cited 29. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

We report here the stereoselective bioreduction of -nitro ketones catalyzed by ketoreductases (KREDs) with publicly known sequences. YGL039w and RasADH/SyADH were able to reduce 23 class I substrates (1-aryl-2-nitro-1-ethanone (1)) and ten class II substrates (1-aryloxy-3-nitro-2-propanone (4)) to furnish both enantiomers of the corresponding -nitro alcohols, with good-to-excellent conversions (up to >99%) and enantioselectivities (up to >99% ee) being achieved in most cases. To the best of our knowledge, KRED-mediated reduction of class II -nitro ketones (1-aryloxy-3-nitro-2-propanone (4)) is unprecedented. Select -nitro alcohols, including the synthetic intermediates of bioactive molecules (R)-tembamide, (S)-tembamide, (S)-moprolol, (S)-toliprolol and (S)-propanolol, were stereoselectively synthesized in preparative scale with 42% to 90% isolated yields, showcasing the practical potential of our developed system in organic synthesis. Finally, the advantage of using KREDs with known sequence was demonstrated by whole-cell catalysis, in which -nitro alcohol (R)-2k, the key synthetic intermediate of hypoglycemic natural product (R)-tembamide, was produced in a space-time yield of 178 g L-1 d(-1) as well as 95% ee by employing the whole cells of a recombinant E. coli strain coexpressing RasADH and glucose dehydrogenase as the biocatalyst.

Application In Synthesis of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Wang, ZX; Wu, XF; Li, ZN; Huang, ZD; Chen, F or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Authors Guan, D; Luan, HX; Patiguli, M; Jiao, QJ; Yun, QQ; Chen, QS; Xu, CJ; Nie, XB; Hu, FP; Huang, GS in WILEY-V C H VERLAG GMBH published article about COUPLING REACTIONS; C5 HALOGENATION; BOND FORMATION; COPPER; QUINOLINES; CHEMISTRY; HALIDES; FLUORINE in [Guan, Dan; Luan, Huo-Xin; Patiguli, Maimaiti; Jiao, Qiu-Ju; Yun, Qing-Qing; Chen, Quan-Sheng; Xu, Chong-Jun; Nie, Xiao-Bin] Xinjiang Lab Petr Reserve Conglomerate, Kalamay 834000, Peoples R China; [Guan, Dan; Luan, Huo-Xin; Patiguli, Maimaiti; Jiao, Qiu-Ju; Yun, Qing-Qing; Chen, Quan-Sheng; Xu, Chong-Jun; Nie, Xiao-Bin] Petrochina Co Ltd, Exp & Testing Res Xinjiang Oilfield Co, Res Inst Enhance Oil Recovery, Kelamayi 834000, Xinjiang, Peoples R China; [Hu, Fang-Peng; Huang, Guo-Sheng] Lanzhou Univ, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Dept Chem, Lanzhou 730000, Gansu, Peoples R China in 2019.0, Cited 40.0. Safety of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

An efficient, metal-free C-H halogenated method for the synthesis of beta-halogenated carboxamides using non-corrosive NXS (X=Cl, Br) as the halogenated source and ammonium sulfocyanide (NH4SCN) as the additive was proposed and accomplished. Various substituted 2-oxazolines efficiently afforded the corresponding beta-halogenated carboxamides via a ring-opening reaction in good yields. The characteristic features of this reaction include readily available materials, mild reaction conditions and functional groups tolerance.

About 3-Methylbenzoic acid, If you have any questions, you can contact Guan, D; Luan, HX; Patiguli, M; Jiao, QJ; Yun, QQ; Chen, QS; Xu, CJ; Nie, XB; Hu, FP; Huang, GS or concate me.. Safety of 3-Methylbenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2021 ORG LETT published article about LACTONIZATION in [Liu, Yang; Battaglioli, Simone; Lombardi, Lorenzo; Menichetti, Arianna; Valenti, Giovanni; Montalti, Marco; Bandini, Marco] Univ Bologna, Alma Mater Studiorum, Dipartimento Chim Giacomo Ciamician, I-40126 Bologna, Italy; [Bandini, Marco] Consorzio CINMPIS, I-40126 Bologna, Italy in 2021, Cited 47. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Application In Synthesis of 3-Methylbenzoic acid

The visible-light photoredox/[Co(III)] cocatalyzed dehydrogenative functionalization of cyclic and acyclic styryl derivatives with carboxylic acids is documented. The methodology enables the chemo- and regioselective allylic functionalization of styryl compounds, leading to allylic carboxylates (32 examples) under stoichiometric acceptorless conditions. Intermolecular as well as intramolecular variants are documented in high yields (up to 82%). A mechanistic rationale is also proposed on the basis of a combined experimental and spectroscopic investigation.

About 3-Methylbenzoic acid, If you have any questions, you can contact Liu, Y; Battaglioli, S; Lombardi, L; Menichetti, A; Valenti, G; Montalti, M; Bandini, M or concate me.. Application In Synthesis of 3-Methylbenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com