Category: isothiazole

Davis, Frankin A.; Haque, M. Serajul published the artcile< Stereochemistry of the asymmetric oxidation of ketone enolates using (camphorylsulfonyl)oxaziridines>, Application In Synthesis of 104322-63-6, the main research area is asym oxidation ketone enolate camphorylsulfonyloxaziridine; chiral hydroxy ketone preparation.

Ketones (e.g., PhCOCH2R; R = Me, Ph) were converted to their enolates with a base, e.g., (Me3Si)2NNa, and then oxidized with chiral oxaziridines, e.g., I, to give chiral hydroxy ketones, e.g. (+)(R)- and (-)(S)-PhCOCH(OH)R, in 69-95% enantiomeric excess and yields as high as 88%. Generally, sodium enolates gave the highest enantiomeric excess. A mechanism is proposed to account for the chiral recognition.

Journal of Organic Chemistrypublished new progress about Enols Role: RCT (Reactant), RACT (Reactant or Reagent). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Application In Synthesis of 104322-63-6.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Bunnage, Mark E.; Chernega, Alexander N.; Davies, Stephen G.; Goodwin, Christopher J. published the artcile< Asymmetric synthesis of β-amino-α-hydroxy acids via diastereoselective hydroxylation of homochiral β-amino enolates>, Name: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide, the main research area is amino hydroxy acid stereoselective preparation; alkenoate conjugate addition amine; enolate amino preparation stereoselective hydroxylation.

The highly diastereoselective conjugate addition of lithium N-benzyl-N-α-methylbenzylamide with enoate acceptors, and the electrophilic hydroxylation of the resultant β-amino enolates with (camphorsulfonyl)oxaziridine, is identified as a direct and general strategy for the asym. synthesis of homochiral β-amino-α-hydroxy acids and their derivatives A structurally diverse array of β-amino enolate substrates can be hydroxylated with generally excellent anti diastereoselectivity (>90% d.e.) using this protocol; an alternative stepwise hydroxylation procedure, where the β-amino enolate is prepared by enolization of the preformed conjugate adduct also led to the anti diastereoisomer. The diastereofacial selectivity of enolate hydroxylation appears to be under predominantly substrate-controlled asym. induction, although a measurable degree of chirality recognition with the oxaziridine reagent can be observed Homochiral β-amino-α-keto esters are also prepared and their stereoselective reductions examined

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999)published new progress about Amino acids, hydroxy Role: SPN (Synthetic Preparation), PREP (Preparation). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Name: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Davis, Franklin A.; Sheppard, Aurelia C. published the artcile< Oxidation of enamines to α-hydroxy ketones and α-amino ketones using N-sulfonyloxaziridines>, Name: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide, the main research area is enamine oxidation sulfonyloxaziridine; ketone hydroxy amino.

Tri-substituted enamines are oxidized to α-hydroxy ketones by N-sulfonyloxaziridines while di-substituted enamines are oxidized to α-amino ketones. A unified mechanism for the formation of both α-hydroxy ketones and α-amino ketones is proposed.

Tetrahedron Letterspublished new progress about Amines, keto Role: SPN (Synthetic Preparation), PREP (Preparation). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Name: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Hewawasam, Piyasena; Meanwell, Nicholas A.; Gribkoff, Valentin K.; Dworetzky, Steven I.; Boissard, Christopher G. published the artcile< Discovery of a novel class of BK channel openers: enantiospecific synthesis and BK channel opening activity of 3-(5-chloro-2-hydroxyphenyl)-1,3-dihydro-3-hydroxy-6-(trifluoromethyl)-2H-indol-2-ones>, Reference of 104322-63-6, the main research area is indolone hydroxy hydroxyphenyl preparation BK channel; BK channel opener hydroxyindolone hydroxyphenyl derivative; structure activity hydroxyphenylindolone BK channel openers.

3-Aryl-3-hydroxyindol-2-ones have been identified as a novel class of BK channel openers. Synthesis of both racemic and chiral 3-aryl-3-hydroxyindolones is described along with their electrophysiol. evaluation as activators of the cloned BK channel mSlo expressed in Xenopus laevis oocytes. The preliminary SAR data indicate the importance of both an electron-withdrawing substituent on the oxindole nucleus and the phenolic hydroxyl for expression of BK channel opening properties. Moreover, the dependence of BK channel opening activity on the absolute configuration of the chiral center in this pharmacophore has been demonstrated.

Bioorganic & Medicinal Chemistry Letterspublished new progress about Potassium channel openers (BK). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Reference of 104322-63-6.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Aluminum(III) sulfate xhydrate, is researched, Molecular Al2H8O13S3, CAS is 17927-65-0, about Concentration of nitric acid by crystallization of hydrates.Recommanded Product: 17927-65-0.

The concentration of dilute HNO3 solutions by crystallization of hydrates of K, Na, Ca, Mg, Fe, and Al sulfates was studied. Pos. results were obtained only with Al2(SO4)3. Anhydrous Al2(SO4)3 was added to 40-60% HNO3 solution at 90-5°. Cooling to 25-30° precipitated Al2(SO4)3-hydrate from which HNO3 was separated by filtration or distillation at 100-50 mm pressure to give 73.5-5.8% HNO3 solution The yield was 93.5-4.8%.

The article 《Concentration of nitric acid by crystallization of hydrates》 also mentions many details about this compound(17927-65-0)Recommanded Product: 17927-65-0, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 17927-65-0, is researched, SMILESS is O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.[H]O[H].[Al].[Al], Molecular Al2H8O13S3Journal, Cement and Concrete Research called Solid solution between Al-ettringite and Fe-ettringite (Ca6[Al1-xFex(OH)6]2(SO4)3·26H2O), Author is Moschner, Goril; Lothenbach, Barbara; Winnefeld, Frank; Ulrich, Andrea; Figi, Renato; Kretzschmar, Ruben, the main research direction is solid solution aluminum iron ettringite phase composition.Category: isothiazole.

The solid solution between Al- and Fe-ettringite Ca6[Al1-xFex(OH)6]2(SO4)3·26H2O was investigated. Ettringite phases were synthesized at different Al/(Al + Fe)-ratios (= XAl,total), so that XAl increased from 0.0 to 1.0 in 0.1 unit steps. After 8 mo of equilibration, the solid phases were analyzed by X-ray diffraction (XRD) and thermogravimetric anal. (TGA), while the aqueous solutions were analyzed by inductively coupled plasma optical emission spectroscopy (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). XRD analyses of the solid phases indicated the existence of a miscibility gap between XAl,total = 0.3-0.6. Some of the XRD reflections showed two overlapping peaks at these molar ratios. The composition of the aqueous solutions, however, would have been in agreement with both, the existence of a miscibility gap or a continuous solid solution between Al- and Fe-ettringite, based on thermodn. modeling, simulating the exptl. conditions.

The article 《Solid solution between Al-ettringite and Fe-ettringite (Ca6[Al1-xFex(OH)6]2(SO4)3·26H2O)》 also mentions many details about this compound(17927-65-0)Category: isothiazole, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Formula: C5H7N3S. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Amino-6-methylpyrimidine-4-thiol, is researched, Molecular C5H7N3S, CAS is 6307-44-4, about Synthesis and Plant Growth Stimulating Action of 2-Amino-6-methylpyrimidine-4(3H)-thione Derivatives. Author is Hambardzumyan, E. N.; Vorskanyan, A. S.; Shahbazyan, L. V.; Yengoyan, A. P..

A series of new pyrimidine derivatives, e.g., I including those containing an azole or azine heterocycle linked through a sulfur atom or a thiomethylene group, was synthesized based on 2-amino-6-methylpyrimidine-4(3H)-thione. The synthesized compounds exhibited a pronounced stimulating effect on plants growth in the range of 43-96% compared to heteroauxin.

The article 《Synthesis and Plant Growth Stimulating Action of 2-Amino-6-methylpyrimidine-4(3H)-thione Derivatives》 also mentions many details about this compound(6307-44-4)Formula: C5H7N3S, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Aluminum(III) sulfate xhydrate(SMILESS: O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.[H]O[H].[Al].[Al],cas:17927-65-0) is researched.Formula: C5H7N3S. The article 《Application of high rate ballasted flocculation technology in wet weather flow treatment》 in relation to this compound, is published in WEFTEC ’99, Annual Conference & Exposition, 72nd, New Orleans, Oct. 9-13, 1999. Let’s take a look at the latest research on this compound (cas:17927-65-0).

An innovative treatment technol. to address wet weather events is the ballasted flocculation process (e.g. Actiflo/Microsep from USFilter). The principal benefits of a ballasted flocculation treatment system for wet weather flows include vastly reduced space requirements, rapid start-up and response times, relative insensitivity to fluctuations in raw water quality, and removal rates greater than conventional systems. The key behind the ballasted flocculation process is the use of continuously recycled ballast or fine sand, which attaches to a flocculated particle through a polymer bridge. The addition of ballast provides 2 benefits: the high sp. gr. sand weights flocculated particles leading to much faster solids settling, and the increase in collision frequencies between sand and flocculated particles dramatically increases flocculation kinetics, resulting in very short mixing times. With rapid particulate settling and flocculation kinetics in ballasted flocculation systems, process design must focus on several fundamental parameters within the clarifier to maximize removal efficiencies and minimize plant footprint. This design approach was adopted in pilot testing of the USFilter ballasted flocculation process during wet weather flows at a variety of sites from 1997 through 1999. High quality, consistent effluent characteristics were achieved despite varying influent conditions. High quality effluent was produced within minutes of start-up, ideal for addressing transient wet weather or peaking events. Removal efficiencies through the ballasted flocculation process of over 85% for total suspended solids and over 60% for BOD were demonstrated. Even with a total hydraulic retention time of 6 min, sufficient residence time for mixing and flocculation was available, resulting in a very small footprint approach for wet weather treatment. With high levels of solids removal in a compact footprint, ballasted flocculation provides a cost competitive alternative to conventional clarification and biol. systems for treating wet weather flows.

The article 《Application of high rate ballasted flocculation technology in wet weather flow treatment》 also mentions many details about this compound(17927-65-0)Recommanded Product: 17927-65-0, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Computed Properties of C10H16O4. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid, is researched, Molecular C10H16O4, CAS is 560-09-8, about Spontaneous Resolution to Absolute Chiral Induction: Pseudo-Kagome Type Homochiral Zn(II)/Co(II) Coordination Polymers with Achiral Precursors. Author is Bisht, Kamal Kumar; Suresh, Eringathodi.

Conglomerate crystallization of achiral precursors yielding racemate metal organic frameworks/coordination polymers (MOFs/CPs) can be driven to absolute homochiral crystallization of the desired enantiomorph by using a suitable chiral induction agent. In crystallization experiments isostructural Zn and Co homochiral CPs (1P, 1M and 2P, 2M) were prepared using the achiral precursors. In the presence of enantiopure camphoric acid, the crystallization process prefers absolute chiral induction over conglomerate formation which is established by single crystal x-ray diffraction and CD spectroscopy. Crystallog. data are given.

The article 《Spontaneous Resolution to Absolute Chiral Induction: Pseudo-Kagome Type Homochiral Zn(II)/Co(II) Coordination Polymers with Achiral Precursors》 also mentions many details about this compound(560-09-8)Computed Properties of C10H16O4, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Molten salt synthesis of mullite nanowhiskers using different silica sources, published in 2015-08-31, which mentions a compound: 17927-65-0, Name is Aluminum(III) sulfate xhydrate, Molecular Al2H8O13S3, Category: isothiazole.

Mullite nanowhiskers with Al-rich structure were prepared by molten salt synthesis at 1000°C for 3 h in air using silica, amorphous silica, and ultrafine silica as the silica sources. The phase and morphol. of the synthesized products were investigated by X-ray diffraction, SEM, energy dispersive spectroscopy, and transmission electron microscopy. A thermogravimetric and DTA was carried out to determine the reaction mechanism. The results reveal that the silica sources play an important role in determining the morphol. of the obtained mullite nanowhiskers. Clusters and disordered arrangements are obtained using common silica and amorphous silica, resp., whereas the use of ultrafine silica leads to highly ordered mullite nanowhiskers that are 80-120 nm in diameter and 20-30 μm in length. Considering the growth mechanisms, mullite nanowhiskers in the forms of clusters and highly ordered arrangements can be attributed to heterogeneous nucleation, whereas disordered mullite nanowhiskers are obtained by homogenous nucleation.

The article 《Molten salt synthesis of mullite nanowhiskers using different silica sources》 also mentions many details about this compound(17927-65-0)Category: isothiazole, you can pay attention to it, because details determine success or failure

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com