Tag: M.W=100-150

COA of Formula: C8H10O2. Singh, DK; Prasad, SS; Kim, J; Kim, I in [Kim, Ikyon] Yonsei Univ, Coll Pharm, 85 Songdogwahak Ro, Incheon 21983, South Korea; Yonsei Univ, Yonsei Inst Pharmaceut Sci, 85 Songdogwahak Ro, Incheon 21983, South Korea published One-pot, three-component approach to diarylacetonitriles in 2019, Cited 56. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

Described herein is a novel one-pot, three-component reaction where aldehydes, electron-rich arenes, and TMSCN in the presence of BF3-OEt2 allowed direct access to a number of diarylacetonitriles under mild reaction conditions in good to excellent yields. Implementation of this assembly protocol to a concise synthetic approach to shoreaphenol, a bioactive oligostilbenoid natural product, is also demonstrated.

COA of Formula: C8H10O2. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Singh, DK; Prasad, SS; Kim, J; Kim, I or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Jeronimo, LB; da Costa, JS; Pinto, LC; Montenegro, RC; Setzer, WN; Mourao, RHV; da Silva, JKR; Maia, JGS; Figueiredo, PLB in [Jeronimo, Lucas Botelho] Univ Estado Para, Campus Barcarena, Barcarena, Brazil; [da Costa, Jamile S.] Univ Fed Para, Programa Posgrad Ciencias Farmaceut, Belem, Para, Brazil; [Pinto, Laine C.] Univ Fed Para, Hosp Univ Joao de Banos Barreto, Lab Neuropatol Expt, Belem, Para, Brazil; [Montenegro, Raquel C.] Univ Fed Ceara, Lab Farmacogenet, Fortaleza, Ceara, Brazil; [Setzer, William N.] Univ Alabama Huntsville, Dept Chem, Huntsville, AL 35899 USA; [Setzer, William N.; da Silva, Joyce Kelly R.] Aromat Plant Res Ctr, Lehi, UT USA; [Veras Mourao, Rosa Helena] Univ Fed Oeste Para, Lab Bioprospeccao & Biol Expt, Santarem, Brazil; [da Silva, Joyce Kelly R.] Univ Fed Para, Programa Posgrad Biotectiol, Belem, Para, Brazil; [Maia, Jose Guilherme S.] Univ Fed Maranhao, Programa Posgrad Quim, Sao Luis, Maranhao, Brazil; [Figueiredo, Pablo Luis B.] Univ Estado Para, Ctr Ciencias Sociais & Educ, Dept Ciencias Nat, Belem, Para, Brazil published Antioxidant and Cytotoxic Activities of Myrtaceae Essential Oils Rich in Terpenoids From Brazil in 2021, Cited 43. COA of Formula: C8H10O2. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

This work analyzed the chemical compositions and evaluated the antioxidant and cytotoxic activities of essential oils (EO) of Eugenia patrisii (Epat), Eugenia stipitata (Esti), Myrcia splendens (Mspl), Myrcia sylvatica (Msyl), Psidium guajava (Pgua), and Psidium guineense (Pgui-1 and Pgui-2) from the Brazilian Amazon. Sesquiterpenoids were found in high concentrations in the oils of E. patrisii and M. splendens, which were rich in E-caryophyllene (32.0% and 45.8%); E. stipitata and M. sylvatica, which displayed germacrene D (11.8%) and germacrene B (24.5%); and P. guajava that showed epi-beta-bisabolol (16.1%) as the main compound. However, P. guineense samples (Pgui-1 and Pgui-2) were rich in monoterpenoids such as limonene (Pgui-1: 30.2%; Pgui-2 30.4%) and alpha-pinene (Pgui-1: 22.5%; Pgui-2: 17.7%). The samples showed a weak and moderate antioxidant activities in the DPPH assay, displaying inhibition rates from 11.5% to 38.6% (at 10 mg/mL). All samples were cytotoxic against human cancer cells by the MTT method. Epat oil showed higher activity against melanoma (SKMEL-19, IC(50)5.8 mu g/mL), gastric (AGP01, IC(50)3.2 mu g/mL), and colon (HCT116, IC(50)6.7 mu g/mL). Meanwhile, the samples Pgua and Pgui were more active against breast cancer cells (MCF7, IC(50)12.4 mu g/mL and 11.6 mu g/mL, respectively).

COA of Formula: C8H10O2. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Jeronimo, LB; da Costa, JS; Pinto, LC; Montenegro, RC; Setzer, WN; Mourao, RHV; da Silva, JKR; Maia, JGS; Figueiredo, PLB or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Category: isothiazole. Recently I am researching about C-H BORYLATION; FUNCTIONALIZATION; IMIDAZOLIUM; COMPLEXES; EFFICIENT; DIBORON, Saw an article supported by the SERB (DST) of India [EMR/2017/000772]; IISER Kolkata. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Das, A; Hota, PK; Mandal, SK. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene

In this study, C(sp(2))-H borylation of arenes was accomplished by a nickel catalyst, resulting in good yield. Alkyl and alkoxy arenes were successfully functionalized, affording C(sp(2))-H borylated compounds. It was unraveled that the well-defined abnormal N-heterocyclic carbene based Ni(II) complex breaks into Ni nanoparticles (Ni-NPs), which act as catalytically active species. A series of controlled reactions under stoichiometric conditions along with spectroscopic studies and single-crystal X-ray crystallographic study helped us to understand the formation of Ni-NPs along with formation of a boron(III) compound during this reaction.

Category: isothiazole. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Das, A; Hota, PK; Mandal, SK or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Ni-Catalyzed Carboxylation of C(sp(2))-S Bonds with CO2: Evidence for the Multifaceted Role of Zn WOS:000513099200047 published article about C-H BONDS; CARBON-DIOXIDE; ELECTROCHEMICAL CONVERSION; ORGANOZINC REAGENTS; ARYLSULFONIUM SALTS; ELECTRON-DONORS; ARYL HALIDES; CHLORIDES; CARBOZINCATION; TRANSFORMATION in [Somerville, Rosie J.; Martin, Ruben] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain; [Martin, Ruben] ICREA, Barcelona 08010, Spain; [Yanagi, Tomoyuki; Nogi, Keisuke; Yorimitsu, Hideki] Kyoto Univ, Grad Sch Sci, Dept Chem, Kyoto 6068502, Japan; [Somerville, Rosie J.] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, E-43007 Tarragona, Spain in 2020.0, Cited 79.0. Quality Control of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

Nickel-catalyzed reductive carboxylation reactions of aryl electrophiles typically require the use of metallic reducing agents. At present, the prevailing perception is that these serve as both a source of electrons and as a source of Lewis acids that may aid CO2 insertion into the Ni-C bond. Herein, we provide evidence for the in situ formation of organometallic species from the metallic reductant, a step that has either been ruled out or has been unexplored in catalytic carboxylation reactions with metal powder reductants. Specifically, we demonstrate that Zn(O) acts as a reductant and that Zn(II) generates arylzinc species that might play a role in the C(sp(2))-S carboxylation of arylsulfonium salts. Overall, the reductive Ni-catalyzed C(sp(2))-S carboxylation reaction proceeds under mild conditions in a non-amide solvent, displays a wide substrate scope, and can be applied to the formal para C-H carboxylation of arenes.

Quality Control of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Yanagi, T; Somerville, RJ; Nogi, K; Martin, R; Yorimitsu, H or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Category: isothiazole. I found the field of Chemistry very interesting. Saw the article Oxidative umpolung selenocyanation of ketones and arenes: An efficient protocol to the synthesis of selenocyanates published in 2020, Reprint Addresses Xiao, JA; Huang, YM (corresponding author), Nanning Normal Univ, Guangxi Key Lab Nat Polymer Chem & Phys, Nanning 530001, Peoples R China.. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene.

A practical method for the umpolung selenocyanation of aryl ketones, alkyl ketones, beta-ketoesters and electron-rich arenes has been developed, affording various selenocyanates in moderate to excellent yields. This transformation proceeds by an oxidative umpolung selenocyanation through nitrogen oxides-mediated electrophilic selenocyanation process. This method is simpler, more efficient, and less costly than precedent methods. Further transformations of the arylselenocyanate was performed to prove the synthetic utility of this methodology. (C) 2020 Elsevier Ltd. All rights reserved.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Cui, JG; Wei, MZ; Pang, LP; Xiao, JA; Gan, CF; Guo, JL; Xie, CF; Zhu, QM; Huang, YM or concate me.. Category: isothiazole

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Zhao, GK; Samanta, SS; Michieletto, J; Roche, SP in [Zhao, Guangkuan; Samanta, Shyam S.; Michieletto, Jessica; Roche, Stephane P.] Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA; [Roche, Stephane P.] Florida Atlantic Univ, Ctr Mol Biol & Biotechnol, Jupiter, FL 33458 USA published A Broad Substrate Scope of Aza-Friedel-Crafts Alkylation for the Synthesis of Quaternary alpha-Amino Esters in 2020, Cited 65. Name: 1,3-Dimethoxybenzene. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

A versatile synthetic protocol of aza-Friedel-Crafts alkylation has been developed for the synthesis of quaternary alpha-amino esters. This operationally simple alkylation proceeds under ambient conditions with high efficiency, regioselectivity, and an exceptionally broad scope of arene nucleophiles. A key feature of this alkylation is the role associated with the silver(I) salt counteranions liberated during the reaction. Taking advantage of a phase-transfer counteranion/Bronsted acid pair mechanism, we also report a catalytic enantioselective example of the reaction.

Name: 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Zhao, GK; Samanta, SS; Michieletto, J; Roche, SP or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Application In Synthesis of 1,3-Dimethoxybenzene. In 2019 GREEN CHEM published article about QUANTUM DOTS; PHOTOREDOX CATALYSIS; GRAPHENE OXIDE; NANODOTS in [Sarma, Daisy; Majumdar, Biju; Sarma, Tridib K.] Indian Inst Technol Indore, Sch Basic Sci, Discipline Chem, Khandwa Rd, Indore 453552, India in 2019, Cited 39. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

The development of carbonaceous materials as metal-free catalysts integrating different types of catalysis in a single system represents a significant advance in cascade/tandem organic synthesis. Zero-dimensional carbon dots with tuneable optical properties and easily modifiable surface functionalities can be harnessed as a carbocatalyst for merging photooxidation and acid-catalyzed reactions in one pot. Herein, we explore carbon dots decorated with hydrogen sulfate groups as a photocatalyst for the dehydrogenative cross-coupling of xanthenes with ketones, arenes and 1,3-dicarbonyl compounds that showed high efficiency and selectivity under visible-light irradiation. The sulphated carbon dots demonstrate dual catalytic properties, wherein they induced the rapid photooxidation of xanthenes in the presence of molecular oxygen to form a hydroperoxy intermediate followed by coupling of nucleophiles catalysed by the acidic surface functional groups. The methodology represents an operationally simple pathway for the generation of C-C coupling products in a short reaction time with wide substrate scopes under mild conditions. The catalyst is easily separable and can be reused over multiple cycles with good efficiency.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Sarma, D; Majumdar, B; Sarma, TK or concate me.. Application In Synthesis of 1,3-Dimethoxybenzene

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Name: 3-Methylbenzoic acid. I found the field of Chemistry very interesting. Saw the article Visible-Light-Induced Deoxygenation/Defluorination Protocol for Synthesis of gamma,gamma-Difluoroallylic Ketones published in 2020.0, Reprint Addresses Wang, QM (corresponding author), Nankai Univ, Coll Chem, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.; Wang, QM (corresponding author), Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid.

Herein, we describe an efficient, practical photocatalytic deoxygenation/defluorination protocol for the synthesis of gamma,gamma-difluoroallylic ketones from commercially available aromatic carboxylic acids, triphenylphosphine, and alpha-trifluoromethyl alkenes. The protocol has good functional group tolerance and a broad substrate scope. Using this method, we accomplished the late-stage functionalization of several bioactive molecules.

Name: 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Guo, YQ; Wang, RG; Song, HJ; Liu, YX; Wang, QM or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Safety of 1,3-Dimethoxybenzene. I found the field of Chemistry very interesting. Saw the article FeCl3-catalyzed three-component aryl-selenylation of alkenes published in 2021, Reprint Addresses He, Z; Zeng, QL (corresponding author), Chengdu Univ Technol, Coll Mat Chem & Chem Engn, State Key Lab Geohazard Prevent & Geoenvironm Pro, Chengdu 610059, Peoples R China.. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene.

FeCl3-catalyzed three-component aryl-selenylation of alkenes with good to excellent yields has been disclosed. This method is characterized by synthesis of complicated products in a single-step reaction, simple operation and readily available commercially reagents. Finally, a reasonable mechanism of FeCl3-catalyzed aryl-selenylation is proposed. (C) 2021 Elsevier Ltd. All rights reserved.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Xu, C; He, Z; Yang, HQ; Chen, HY; Zeng, QL or concate me.. Safety of 1,3-Dimethoxybenzene

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

COA of Formula: C8H10O2. In 2019 EUR J INORG CHEM published article about N-HETEROCYCLIC CARBENES; STRUCTURAL IMPLICATIONS; ELECTROPHILES; METHYLATION; COMPLEXES; PHOSPHINE; ANISOLES; ALLENE; LIGAND in [Ambre, Ram; Yang, Hsuan; Chen, Wen-Ching; Ong, Tiow-Gan] Acad Sinica, Inst Chem, 128,Sec 2,Acad Rd, Taipei, Taiwan; [Yap, Glenn P. A.] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA; [Jurca, Titel] Univ Cent Florida, Dept Chem, 4111 Libra Dr, Orlando, FL 32816 USA; [Jurca, Titel] Univ Cent Florida, Renewable Energy & Chem Transformat Cluster, 4353 Scorpius St, Orlando, FL 32816 USA; [Ong, Tiow-Gan] Natl Chiao Tung Univ, Dept Appl Chem, 1001 Ta Hsueh Rd, Hsinchu, Taiwan; [Ong, Tiow-Gan] Natl Taiwan Univ, Dept Chem, 1,Sec 4,Roosevelt Rd, Taipei, Taiwan in 2019, Cited 65. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

The development of a cross-coupling reaction protocol between aryl ethers and Grignard reagents catalyzed by carbodicarbene (CDC) nickel complexes to afford biaryl compounds through C-O cleavage is reported. Aromatic substrates featuring a broad range of electron neutral, donating, or withdrawing groups are introduced at the desired position. The method has proven effective over a wide range of naphthyl methyl ethers, anisoles, and Grignard reagents. The robustness of the protocol is validated by performing multiple cleavage reactions, gram scale synthesis, and arylation of a dimethoxy esterdiol derivative.

COA of Formula: C8H10O2. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Ambre, R; Yang, H; Chen, WC; Yap, GPA; Jurca, T; Ong, TG or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com