Tag: M.W=100-150

An article Controlling reactivity in the Fujiwara-Moritani reaction: Examining solvent effects and the addition of 1,3-dicarbonyl ligands on the oxidative coupling of electron rich arenes and acrylates WOS:000512482000005 published article about C-H OLEFINATION; BOND ACTIVATION; CATALYZED OLEFINATION; AROMATIC-SUBSTITUTION; MIZOROKI-HECK; PD; ARYLATION; ALKENYLATION; DERIVATIVES; ETHYLENE in [Jones, Roderick C.] Univ Coll Dublin, Sch Chem & Bioproc Engn, Dublin 4, Ireland in 2020, Cited 73. Recommanded Product: 1,3-Dimethoxybenzene. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

A palladium-catalysed direct alkenation of electron rich arenes in the presence of K2S2O8 with an acetic acid/1,4-dioxane solvent combination has been developed. The 1,4-dioxane co-solvent dramatically influences the rate of reaction, giving selectively disubstituted alkenes, while the addition of acetylacetone ligands was shown to increase site selectivity for the alkenation of monofunctionalized arenes. The participation of these carbonyl ligands has been confirmed by ESI-MS studies, with some key in situ intermediates in the catalytic cycle identified. A variety of electron rich arenes and olefinic substrates can be utilised in the direct oxidative coupling to give disubstituted alkenes in moderate to good yields. (C) 2019 Elsevier Ltd. All rights reserved.

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Luo, WP; Shi, SL; Shen, ZP; Guan, AC; Yang, LT; Yang, WJ in [Shi, Sile; Shen, Zhipeng; Guan, Aocong; Yang, Lintao; Yang, Weijun] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China; [Luo, Weiping] Hunan Univ, Coll Chem & Chem Engn, Minist Educ, Adv Catalyt Engineer Res Ctr, Changsha 410082, Peoples R China published New Group Interaction Parameters of the UNIFAC (Dortmund) Model: Aromatic Dicarboxylic Acid Isomer and Methyl Benzoic Acid Isomer Binaries in 2020, Cited 29. Category: isothiazole. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

In this work, with the available solid-liquid equilibrium (SLE) data of six aromatic carboxylic acids, aromatic dicarboxylic acid isomers (terephthalic acid (TPA), isophthalic acid (IPA), and phthalic acid (PA)), and methyl benzoic acid isomers (m-toluic acid (m-TA), o-toluic acid (o-TA), and p-toluic acid (p-TA)) in acetic acid (HOAc) + water (H2O) solvent mixtures, the relationship between the molecular structure of the above aromatic carboxylic acids and the solubility of them in HOAc + H2O solvent mixtures is discussed. It could be found that among the aromatic dicarboxylic acid isomers and methyl benzoic acid isomers, TPA and p-TA have the lowest solubility in the same solvent and temperature, respectively. Meanwhile, three new groups, p-ArCOOH, m-ArCOOH, and o-ArCOOH, in the UNIFAC (Dortmund) model were first defined to distinguish the influence of the positions of ArCOOH on the thermodynamic properties of aromatic carboxylic acid isomers, which indicates that ArCOOH is located in the para, meta, and ortho positions of the ArCOOH or ArCH3 groups, respectively. Then, the interaction parameters of ArCOOH, p-ArCOOH, m-ArCOOH, and o-ArCOOH with other involved groups in the solvent systems are first obtained by regressing these available SLE data. By using the new defined group, the UNIFAC (Dortmund) model was used to correlate SLE data for the above ternary systems, and trimesic acid + HOAc + H2O systems agree with the experimentally measured results satisfactorily.

About 3-Methylbenzoic acid, If you have any questions, you can contact Luo, WP; Shi, SL; Shen, ZP; Guan, AC; Yang, LT; Yang, WJ or concate me.. Recommanded Product: 3-Methylbenzoic acid

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Isothiazole – Wikipedia,
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SDS of cas: 99-04-7. Authors Xu, KQ; Liu, L; Li, ZH; Huang, TZ; Xiang, K; Chen, TQ in AMER CHEMICAL SOC published article about in [Xu, Kaiqiang; Liu, Long; Li, Zhaohui; Huang, Tianzeng; Xiang, Kang; Chen, Tieqiao] Hainan Univ, Hainan Prov Fine Chem Engn Res Ctr, Hainan Prov Key Lab Fine Chem, Key Lab,Minist Educ Adv Mat Trop Isl Resources, Haikou 570228, Hainan, Peoples R China in 2020, Cited 64. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

The controllable phosphorylations of thioesters were developed. When the reaction was catalyzed by a palladium catalyst, aryl or alkenyl phosphoryl compounds were generated through decarbonylative coupling, while the benzyl phosphoryl compounds were produced through deoxygenative coupling when the reaction was carried out in the presence of only a base.

SDS of cas: 99-04-7. About 3-Methylbenzoic acid, If you have any questions, you can contact Xu, KQ; Liu, L; Li, ZH; Huang, TZ; Xiang, K; Chen, TQ or concate me.

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Isothiazole – Wikipedia,
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Recently I am researching about TRANSPOSON MUTANT LIBRARY; PYOCYANIN; SEQUENCE; MUCOIDY; PROBES; ALGP, Saw an article supported by the Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG) [SI-1096/10-1, WI3285/61]; National Science FoundationNational Science Foundation (NSF) [CHE1755698]; National Institute of General Medical SciencesUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [GM119426]; Cystic Fibrosis FoundationItalian Cystic Fibrosis Research Foundation [MCCART15R0]; NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of Allergy & Infectious Diseases (NIAID) [R21AI122192, F31AI136310] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R35GM119426] Funding Source: NIH RePORTER. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Zhao, WN; Cross, AR; Crowe-McAuliffe, C; Weigert-Munoz, A; Csatary, EE; Solinski, AE; Krysiak, J; Goldberg, JB; Wilson, DN; Medina, E; Wuest, WM; Sieber, SA. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene. Application In Synthesis of 1,3-Dimethoxybenzene

Natural products represent a rich source of antibiotics that address versatile cellular targets. The deconvolution of their targets via chemical proteomics is often challenged by the introduction of large photocrosslinkers. Here we applied elegaphenone, a largely uncharacterized natural product antibiotic bearing a native benzophenone core scaffold, for affinity-based protein profiling (AfBPP) in Gram-positive and Gram-negative bacteria. This study utilizes the alkynylated natural product scaffold as a probe to uncover intriguing biological interactions with the transcriptional regulator AlgP. Furthermore, proteome profiling of a Pseudomonas aeruginosa AlgP transposon mutant provided unique insights into the mode of action. Elegaphenone enhanced the elimination of intracellular P.aeruginosa in macrophages exposed to sub-inhibitory concentrations of the fluoroquinolone antibiotic norfloxacin.

Application In Synthesis of 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Zhao, WN; Cross, AR; Crowe-McAuliffe, C; Weigert-Munoz, A; Csatary, EE; Solinski, AE; Krysiak, J; Goldberg, JB; Wilson, DN; Medina, E; Wuest, WM; Sieber, SA or concate me.

Reference:
Isothiazole – Wikipedia,
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Recently I am researching about ATOM TRANSFER OXIDATION; AROMATIC HALIDES; ALKYL; REDUCTIONS; GENERATION; CATALYSIS; ALKENYL; IODIDES, Saw an article supported by the Singapore National Research FoundationNational Research Foundation, Singapore [NRF-NRFI2016-06]; Ministry of Education of SingaporeMinistry of Education, Singapore [MOE2013-T2-2-003, MOE2016-T2-1-032, RG108/16]; A* STAR Individual Research Grant [A1783c0008]; Nanyang Research Award Grant; Nanyang Technological UniversityNanyang Technological University; Guizhou Province First-Class Disciplines Project (Yiliu Xueke Jianshe Xiangmu) [GNYL(2017)008]; Guiyang College of Traditional Chinese Medicine, China; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772029, 21472028]; National Key Technologies RD ProgramNational Key Technology R&D Program [2014BAD23B01]; 10 Talent Plan (Shicengci) of Guizhou Province; Guizhou University; Thousand Talent Plan. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Ke, J; Wang, HL; Zhou, LJ; Mou, CL; Zhang, JJ; Pan, LT; Chi, YR. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene. Application In Synthesis of 1,3-Dimethoxybenzene

A catalyst- and metal-free electrochemical hydrodehalogenation of aryl halides is disclosed. Our reaction by a flexible protocol is operated in an undivided cell equipped with an inexpensive graphite rod anode and cathode. Trialkylamines nBu(3)N/Et3N behave as effective reductants and hydrogen atom donors for this electrochemical reductive reaction. Various aryl and heteroaryl bromides worked effectively. The typically less reactive aryl chlorides and fluorides can also be smoothly converted. The utility of our method is demonstrated by detoxification of harmful pesticides and hydrodebromination of a dibrominated biphenyl (analogues of flame-retardants) in gram scale.

Application In Synthesis of 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Ke, J; Wang, HL; Zhou, LJ; Mou, CL; Zhang, JJ; Pan, LT; Chi, YR or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Regiodivergent Aromatic Electrophilic Substitution Using Nitrosoarenes in Hexafluoroisopropanol: A Gateway for Diarylamines and p-Iminoquinones Synthesis WOS:000479240800001 published article about C-H AMINATION; ORGANIC-SYNTHESIS; IODINE(V) REAGENTS; BORONIC ACIDS; BRONSTED ACID; BONDS; DELIVERY; NITROSOBENZENES; HETEROCYCLES; DERIVATIVES in [Pradhan, Suman; Roy, Sourav; Ghosh, Soumen; Chatterjee, Indranil] Indian Inst Technol Ropar, Dept Chem, Nangal Rd, Rupnagar 140001, Punjab, India in 2019, Cited 79. Quality Control of 1,3-Dimethoxybenzene. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

A metal-free aromatic electrophilic substitution reaction using nitrosoarenes as the electrophile in 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) is reported. HFIP activates nitrosoarene towards the electrophilic C-H amination followed by a concomitant N-O bond cleavage to deliver diarylamines without requiring any extra reagent or further treatment. The dual electrophilic nature of nitrosoarene permits a switchover of selectivity to C-H oxygenation furnishing dearomatizedp-iminoquinones following a unique mechanistic rationale of two consecutive [2,3] sigmatropic rearrangement in nitroso-chemistry.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Pradhan, S; Roy, S; Ghosh, S; Chatterjee, I or concate me.. Quality Control of 1,3-Dimethoxybenzene

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Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Name: 3-Methylbenzoic acid. In 2020 BIOORG MED CHEM LETT published article about SMALL-MOLECULE INHIBITOR; CARCINOMA IN-VITRO; ALPHA; DERIVATIVES; METABOLISM; ACTIVATOR; SIRTUINS; PATHWAY in [Dukanya; Metri, Prashant K.; Mohan, Surender; Basappa] Univ Mysore, Dept Studies Organ Chem, Lab Chem Biol, Mysore 570006, Karnataka, India; [Shanmugam, Muthu K.] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Singapore 117600, Singapore; [Rangappa, Shobith] Adichunchanagiri Inst Mol Med, Bg Nagara 571448, Nagamangalatalu, India; [Rangappa, Kanchugarakoppal S.] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India in 2020, Cited 33. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

A novel series of indazole tethered oxadiazoles (OTDs) derivatives were synthesized, characterized and screened for their anti-proliferative activity against hepatocellular carcinoma (HCC) cells. OTDs structure was further confirmed by Single-crystal X-ray diffraction studies. Among the tested OTDs, compound 2-(4-methoxyphenyl)-5-(1-methyl-1H-indazol-3-yl)-1,3,4 oxadiazole was found to inhibit the catalytical activity of SIRT2 and brings about apoptosis as shown by western blot analysis and flow cytometry data. Also, the tested OTDs were found to interact with the active site of human SIRT2 in silico but not with the cavity of co-crystal ligand 5-(3- hydroxypropyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole, which indicate that these OTDs has potential in the development of SIRT2 inhibitors in liver cancer models.

About 3-Methylbenzoic acid, If you have any questions, you can contact Dukanya; Shanmugam, MK; Rangappa, S; Metri, PK; Mohan, S; Basappa; Rangappa, KS or concate me.. Name: 3-Methylbenzoic acid

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Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2019 ORG BIOMOL CHEM published article about CATALYZED CYCLOISOMERIZATION; ENANTIOSELECTIVE SYNTHESIS; DENSITY FUNCTIONALS; GOLD CATALYSIS; 1,5-ENYNES; CARBENE; ALKOXYCYCLIZATIONS; 1,3-DIEN-5-YNES; PERFORMANCE; 1,6-ENYNES in [Virumbrales, Cintia; Solas, Marta; Suarez-Pantiga, Samuel; Fernandez-Rodriguez, Manuel A.; Sanz, Roberto] Univ Burgos, Fac Ciencias, Dept Quim, Area Quim Organ, Pza Misael Banuelos S-N, Burgos 09001, Spain; [Marin-Luna, Marta; Silva Lopez, Carlos] Univ Vigo, Dept Quim Organ, AS Lagoas Marcosende S-N, Vigo 36310, Spain; [Silva Lopez, Carlos] Univ Vigo, CITACA, Orense 32004, Spain; [Fernandez-Rodriguez, Manuel A.] Univ Alcala De Henares, Fac Farm, Dept Quim Organ & Quim Inorgan, Campus Cient Tecnol,Autovia A-2,Km 33-1, Madrid, Spain in 2019, Cited 64. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0. SDS of cas: 151-10-0

The stereospecific gold(i)-catalyzed nucleophilic cyclization of beta-monosubstituted o-(alkynyl)styrenes to produce C-1 functionalized 1H-indenes including challenging substrates and nucleophiles, such as beta-(cyclo)alkyl-substituted o-(alkynyl)styrenes and a variety of alcohols as well as selected electron-rich aromatics, is reported. DFT calculations support the stereochemical outcome of the process that involves the formation of a key cyclopropyl gold carbene intermediate through a regiospecific 5-endo cyclization.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Virumbrales, C; Solas, M; Suarez-Pantiga, S; Fernandez-Rodriguez, MA; Marin-Luna, M; Lopez, CS; Sanz, R or concate me.. SDS of cas: 151-10-0

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Category: isothiazole. Authors Prasad, SS; Joshi, DR; Kim, I in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Kim, Ikyon] Yonsei Univ, Coll Pharm, 85 Songdogwahak Ro, Incheon 21983, South Korea; Yonsei Univ, Yonsei Inst Pharmaceut Sci, 85 Songdogwahak Ro, Incheon 21983, South Korea in 2021, Cited 20. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

A direct one-pot access to diarylmethylazides, versatile intermediates, from commercially available starting materials was enabled via three-component coupling of aldehydes, arenes, and TMSN3 in the presence of a catalytic amount of BF3.OEt2. (C) 2021 Elsevier Ltd. All rights reserved.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Prasad, SS; Joshi, DR; Kim, I or concate me.. Category: isothiazole

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Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Application In Synthesis of 3-Methylbenzoic acid. Liu, Y; Battaglioli, S; Lombardi, L; Menichetti, A; Valenti, G; Montalti, M; Bandini, M in [Liu, Yang; Battaglioli, Simone; Lombardi, Lorenzo; Menichetti, Arianna; Valenti, Giovanni; Montalti, Marco; Bandini, Marco] Univ Bologna, Alma Mater Studiorum, Dipartimento Chim Giacomo Ciamician, I-40126 Bologna, Italy; [Bandini, Marco] Consorzio CINMPIS, I-40126 Bologna, Italy published Visible-Light Photoredox Catalyzed Dehydrogenative Synthesis of Allylic Carboxylates from Styrenes in 2021, Cited 47. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

The visible-light photoredox/[Co(III)] cocatalyzed dehydrogenative functionalization of cyclic and acyclic styryl derivatives with carboxylic acids is documented. The methodology enables the chemo- and regioselective allylic functionalization of styryl compounds, leading to allylic carboxylates (32 examples) under stoichiometric acceptorless conditions. Intermolecular as well as intramolecular variants are documented in high yields (up to 82%). A mechanistic rationale is also proposed on the basis of a combined experimental and spectroscopic investigation.

About 3-Methylbenzoic acid, If you have any questions, you can contact Liu, Y; Battaglioli, S; Lombardi, L; Menichetti, A; Valenti, G; Montalti, M; Bandini, M or concate me.. Application In Synthesis of 3-Methylbenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com