Tag: M.W:100-200

272-16-2, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 272-16-2, molecular formula is C7H5NS, introducing its new discovery.

Processes for producing isothiazole derivatives

A method for producing a 1,2-benzisothiazole characterized by treating a 2-(alkylthio)benzaldehyde oxime with a halogen compound; a method for producing a 3-halo-1,2-benzisothiazole characterized by treating a 1,2-benzisothiazole with a halogenating agent; and a method for producing a 1-(1,2-benzisothiazol-3-yl)piperazine characterized by reacting the obtained 3-halo-1,2-benzisothiazoles with a piperazine. By the method of the present invention, 1,2-benzisothiazoles and 3-halo-1,2-benzisothiazoles, which are useful as intermediates for pharmaceutical compositions such as psychotropic agents, and 1-(1,2-benzisothiazole-3-yl)piperazines synthesized therefrom can be obtained in a high yield without using expensive starting materials by shorter and simpler process than conventional methods.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.272-16-2, you can also check out more blogs about272-16-2

Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬Which mentioned a new discovery about 18480-53-0, molcular formula is C4HCl2NO2S, introducing its new discovery. , 18480-53-0

Isothiazole carboxylic acid amides and the application thereof in order to protect plants

Novel isothiazolecarboxamides of the formula in whichR is as defined in the description, a plurality of processes for preparing the novel compounds and their use for protecting plants against attack by undesirable microorganisms and animal pests.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, 18480-53-0, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 18480-53-0

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Isothiazole – Wikipedia,
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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 4576-90-3. In a patent£¬Which mentioned a new discovery about 4576-90-3, molcular formula is C4H3NO2S, introducing its new discovery.

HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS

This invention is directed to pyridine- and thiophene-sulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy and/ or epileptic seizure disorders.

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

111248-89-6, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 111248-89-6, name is 1,3-Dihydrobenzo[c]isothiazole 2,2-dioxide. In an article£¬Which mentioned a new discovery about 111248-89-6

Synthesis and activity of 2-(sulfonamido)methylcarbapenems: Discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore

A series of 1beta-methyl carbapenems substituted at the 2-position with lipophilic, acyclic and cyclic (sulfonamido)methyl groups was prepared and evaluated for activity against resistant gram-positive bacteria. From these studies, the 1,8-naphthosultamyl group emerged as a novel, PBP2a-binding, anti-MRSA pharmacophore worthy of further exploration.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 111248-89-6 is helpful to your research. 111248-89-6

Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, belongs to isothiazole compound, is a common compound. 27148-03-4In an article, authors is Al-Jibori, Subhi A., once mentioned the new application about 27148-03-4.

Palladium(II) benzisothiazolinate (bit) complexes with amino-, acetylamino-, heterocyclic and phosphine co-ligands. Crystal structure of [Pd(bit)2(kappa2-dppe)]¡¤2EtOH

Abstract A series of square-planar palladium(II) benzisothiazolinate (bit) of the general type [Pd(bit)2L2] have been prepared and characterized by analytical and spectroscopic methods. Two synthetic routes have been employed, namely reactions of [Pd(bit)2]¡¤H2O with two equivalents of ligands (L = amine, amide, phosphine) or nucleophile displacement of chloride by benzisothiazolinate starting from trans-[PdCl2L2]. Both routes afford the new complexes in good yields as easily isolated, air and moisture stable, colored solids. The precursor, [Pd(bit)2]¡¤H2O, is itself prepared in high yields upon reaction of Na[bit] with Na2[PdCl4] in methanol and the analogous platinum complex, [Pt(bit)2]¡¤H2O, is similarly prepared from K2[PtCl4]. It is not clear if these species are mono- or dimeric, and formulation as [M2(mu-bit)4(H2O)2] with the four benzisothiazolinate spanning the metal-metal vector and possibly binding through coordination of nitrogen and oxygen is suggested. Diphosphine adducts, cis-[Pd(bit)2{kappa2-Ph2P(CH2)nPPh2}] (n = 1-4) can be prepared both upon addition of the diphosphine to [Pd(bit)2]¡¤H2O and from reactions of cis-[PdCl2{kappa2-Ph2P(CH2)nPPh2}] with two equivalents of Na[bit]. A crystal structure of cis-[Pd(bit)2(kappa2-dppe)] reveals that the benzisothiazolinate ligands are bonded in a monodentate fashion through nitrogen and this binding mode is proposed for all [Pd(bit)2L2] and [Pd(bit)2L] complexes. With dppb (n = 4) a second product is seen by NMR spectroscopy being proposed to be the part-substituted complex cis-[PdCl(bit)(kappa2-dppb)], while with dppm (n = 1) two further products are seen spectroscopically, proposed as trans-[Pd(bit)2(kappa1-dppm)2] and (more tenuously) [Pd2(bit)4(dppm)2]. The former is also prepared in good yields from reaction of [Pd(kappa2-dppm)2]Cl2 with Na[bit]. These studies show that palladium benzisothiazolinate are easily accessed and show good air and moisture stability.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 18480-53-0, molecular formula is C4HCl2NO2S, introducing its new discovery. 18480-53-0

1,2,3-Thiadiazole-3-in-5-ylidene-urea derivatives, process for making the same and compositions containing the same having growth regulating activity for plants

1,2,3-Thiadiazole-3-in-5-ylidene-urea derivative of the formula STR1 in which R1 is hydrogen or alkyl which may be substituted in one or several places by oxygen or sulfur and wherein R2 and R3 have the meaning as given in the attached specification and wherein X is oxygen or sulfur. The compounds have properties suited for controlling the natural growth and natural development of plants and in addition have a superior defoliating property without accompanying unpleasant odors.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

111248-89-6, In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 111248-89-6, name is 1,3-Dihydrobenzo[c]isothiazole 2,2-dioxide, introducing its new discovery.

SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS

The present invention relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts, wherein R 1, R2, R3, R4, R5, and R6 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (k) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.111248-89-6, you can also check out more blogs about111248-89-6

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

An article , which mentions 27148-03-4, molecular formula is C7H5NO2S2. The compound – Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide played an important role in people’s production and life., 27148-03-4

Synthesis and spectroscopic characterization of two new thiosaccharinate salts. Molecular structure of bis(triphenylphosphine)iminium thiosaccharinate, PNP(tsac)

We report the synthesis, FTIR, Raman and NMR spectroscopic features of bis(triphenylphosphine)iminium and tetrabutylammonium thiosaccharinates, PNP(tsac) and NBu 4 (tsac) (tsac: thiosaccharinate anion, PNP: bis(triphenylphosphine)iminium). The molecular structure of the former compound was determined by X-ray diffraction methods. The salt crystallizes in the monoclinic P21/n space group with a = 9.6481(9), b = 29.258(3), c = 13.177(2)?A, beta = 97.53(1), and Z = 4 molecules per unit cell. Slight but significant changes in the bonding structure of the thiosaccharinate anion as compared with those reported for the neutral molecule are observed. Springer-Verlag 2007.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! Read on for other articles about 1273-94-5!, 27148-03-4

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

18480-53-0, In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 18480-53-0, name is 3,4-Dichloroisothiazole-5-carboxylic acid, introducing its new discovery.

Hybrid corn seed and method

A method for hybridizing corn (zea mays) by crossing two corn varieties by rendering a female parent male sterile with an isothiazole plant growth regulator and then pollinating the male sterile female parent with pollen from a second variety.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.18480-53-0, you can also check out more blogs about18480-53-0

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

 

272-16-2, In an article, published in an article,authors is Braibanti, Antonio, once mentioned the application of 272-16-2, Name is Benzo[d]isothiazole,molecular formula is C7H5NS, is a conventional compound. this article was the specific content is as follows.

SPECTROSCOPIC PROPERTIES AND PROTONATION EQUILIBRIA IN 1,2-BENZISOTHIAZOLES

The protonation equilibria of 1,2-benzisothiazoles, involving substituents at position 3, or the ring nitrogen at position 2, have been investigated by potentiometric and/or spectrophotometric methods.The values of the protonation constants (log Kobs) have been compared with values calculated according to the linear relationships of Barlin and Perrin.For compounds with substituents at position 3, the protonation constants have been determined potentiometrically.The presence of the benzisothiazole moiety induces an increase of base strength, with respect to that expected from the calculated substituent effects according to Barlin and Perrin.The protonation constants of the heterocyclic nitrogen at position 2 have been determined spectroscopically in very acidic solutions.The comparison of the values observed with those calculated following Barlin and Perrin for substituted isoquinoline shows that the ring nitrogen is less basic than expected.

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Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com