Tag: M.W=150-200

Name: 2,5-Dimethoxybenzaldehyde. Ravindran, J; Yadhukrishnan, VO; Asha, RS; Lankalapalli, RS in [Ravindran, Jaice; Yadhukrishnan, Velickakathu O.; Asha, Reghuvaran S.; Lankalapalli, Ravi S.] CSIR Natl Inst Interdisciplinary Sci & Technol CS, Chem Sci & Technol Div, Thiruvananthapuram 695019, Kerala, India; [Ravindran, Jaice; Lankalapalli, Ravi S.] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India published Dienaminodioate based multicomponent reactions with post-benzylic oxidative transformations mediated by DDQ in 2020.0, Cited 45.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

Multicomponent reactions (MCRs) using dienaminodioate with post-benzylic oxidative transformation mediated by DDQ that afforded a diverse array of products are described. An unprecedented rearrangement of 1,2-dihydropyridines (1,2-DHPs), 3CR products, to 2-pyridones in good yields with a broad substrate scope by DDQ-mediated benzylic oxidation via a pyridinium intermediate is reported. Treatment of the pyridinium intermediate with tert-butyl isocyanide afforded isomerized 1,2-DHPs, analogous to Ritter amides. Further diversification using 3CR products bearing a benzylic group, predictably, promoted the synthesis of 2-pyridone with a benzylideneamine group and a benzo[d]oxazole appended biaryl group by DDQ. A formal 1,6-reduction product from 2-pyridone in the presence of NaBH4 is also observed.

Name: 2,5-Dimethoxybenzaldehyde. Welcome to talk about 93-02-7, If you have any questions, you can contact Ravindran, J; Yadhukrishnan, VO; Asha, RS; Lankalapalli, RS or send Email.

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Product Details of 93-02-7. Authors Swain, B; Abhay; Singh, P; Angeli, A; Aashritha, K; Nagesh, N; Supuran, CT; Arifuddin, M in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Swain, Baijayantimala; Abhay; Singh, Priti; Aashritha, Kamtam; Arifuddin, Mohammed] Natl Inst Pharmaceut Educ & Res NIPER, Dept Med Chem, Hyderabad 500037, India; [Angeli, Andrea; Supuran, Claudiu T.] Univ Firenze, Neurofarba Dept, Sez Sci Farmaceut & Nutraceut, Via Ugo Schiff 6, I-50019 Florence, Italy; [Arifuddin, Mohammed] Anwarul Uloom Coll, Dept Chem, 11-3-918 New Malleypally, Hyderabad 500001, India; [Nagesh, Narayana] Ctr Cellular & Mol Biol CCMB, Hyderabad, India in 2021, Cited 24. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7

A new series of benzenesulphonamide linked-1,3,4-oxadiazole hybrids (6a?s) has been synthesized and tested for their carbonic anhydrase inhibition against human (h) carbonic anhydrase (CA) isoforms hCA I, II, IX, and XIII. Fluorescence properties of some of the synthesized molecules were studied. Most of the molecules exhibited significant inhibitory power, comparable or better than the standard drug acetazolamide (AAZ) on hCA XIII. Out of 19 tested molecules, compound 6e (75.8 nM) was 3 times more potent than AAZ (250.0 nM) against hCA I, whereas compound 6e (15.4 nM), 6g (16.2 nM), 6h (16.4 nM) and 6i (17.0 nM) were found to be more potent than AAZ (17.0 nM) against isoform hCA XIII. It is anticipated that these compounds could be taken as the potential leads for the development of selective hCA XIII isoform inhibitors with improved potency.

Welcome to talk about 93-02-7, If you have any questions, you can contact Swain, B; Abhay; Singh, P; Angeli, A; Aashritha, K; Nagesh, N; Supuran, CT; Arifuddin, M or send Email.. Product Details of 93-02-7

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In 2019.0 LETT ORG CHEM published article about SOLVENT-FREE SYNTHESIS; HIGHLY EFFICIENT; RECYCLABLE CATALYST; SULFURIC-ACID; IN-SITU; ONE-POT; CONVENIENT; SYSTEM; DERIVATIVES; ALDIMINES in [Soliman, Hanan A.; El-Shahat, Mahmoud] Natl Res Ctr, Photochem Dept, Cairo, Egypt; [Soliman, Abdel-Ghany] Natl Inst Oceanog & Fisheries, Cairo, Egypt in 2019.0, Cited 65.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7. SDS of cas: 93-02-7

A straightforward strategy for the synthesis of N-sulfonyl imine derivatives from sulfona-mides and aryl aldehydes utilizing Silica-supported zinc chloride (ZnCl2/SiO2, silzic) as a catalyst under solvent-free conditions has been developed. 2-Arylbenwthiazole derivatives were also synthesized by the reaction of 2-aminothiophenol with aryl aldehydes under the same conditions. This procedure has advantages of high yields, mild reaction condition, simple procedure, low cost, and simplicity of workup. The catalyst has the same efficiency on its reuse up to three times.

SDS of cas: 93-02-7. Welcome to talk about 93-02-7, If you have any questions, you can contact Soliman, HA; El-Shahat, M; Soliman, AG or send Email.

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Recommanded Product: 2,6-Difluorobenzoic acid. In 2021 ORG LETT published article about INHIBITORS; ALDEHYDES; ACIDS in [Currie, Iain; Sleebs, Brad E.] Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia; [Currie, Iain; Sleebs, Brad E.] Univ Melbourne, Dept Med Biol, Parkville, Vic 3010, Australia in 2021, Cited 24. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2.

A one-step synthesis of acyl phosphoramidates from a variety of functionalized acyl azides has been developed employing trimethylsilyl chloride as an activating agent in a modified Staudinger reaction. The methodology was further adapted to include the in situ generation of the acyl azides from a diverse selection of carboxylic acids and hydrazide starting synthons. The reaction scope was extended to include the synthesis of imidodiphosphates and the natural product Microcin C.

Welcome to talk about 385-00-2, If you have any questions, you can contact Currie, I; Sleebs, BE or send Email.. Recommanded Product: 2,6-Difluorobenzoic acid

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Computed Properties of C9H10O3. Recently I am researching about C-H ACIDS; MULTICOMPONENT REACTIONS; HETEROCYCLIC CHEMISTRY; CARBONYL-COMPOUNDS; BARBITURIC-ACIDS; MALONONITRILE; TRANSFORMATION; CONVENIENT; FACILE; MALONATE, Saw an article supported by the RFBRRussian Foundation for Basic Research (RFBR) [19-29-08013]. Published in ARKAT USA INC in GAINESVILLE ,Authors: Elinson, MN; Ryzhkova, YE; Vereshchagin, AN; Leonova, NA; Minaeva, AP; Egorov, MP. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde

The electrochemically induced tandem reaction of aldehydes and two equivalents of kojic acid has been carried out in alcohols in an undivided cell in the presence of sodium halides. It led to the selective formation of substituted arylbis[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl]methanes in 71-98% yields and with 240-330% current efficiency. This new electrocatalytic process provides green, useful and efficient way to two kojic acid fragments separated by C-aryl-substituted spacer, which are promising compounds for different biomedical applications. [GRAPHICS] .

Computed Properties of C9H10O3. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

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Name: 2,6-Difluorobenzoic acid. Authors Lin, TT; Li, JC; Liu, LP; Li, YQ; Jiang, HL; Chen, KX; Xu, P; Luo, C; Zhou, B in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER published article about in [Lin, Tingting; Jiang, Hualiang; Chen, Kaixian; Luo, Cheng] ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 200031, Peoples R China; [Lin, Tingting; Jiang, Hualiang; Chen, Kaixian; Luo, Cheng] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 200031, Peoples R China; [Lin, Tingting; Li, Jiacheng; Liu, Liping; Li, Yuanqing; Jiang, Hualiang; Chen, Kaixian; Xu, Pan; Luo, Cheng] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Ctr Chem Biol,Drug Discovery & Design Ctr, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; [Lin, Tingting; Zhou, Bing] Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; [Lin, Tingting; Li, Jiacheng; Liu, Liping; Li, Yuanqing; Jiang, Hualiang; Chen, Kaixian; Luo, Cheng; Zhou, Bing] Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China in 2021, Cited 39. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2

Cyclin-dependent kinases play significant roles in cell cycle progression and are promising targets for cancer therapy. However, most potent CDK inhibitors lack the balance between efficacy and safety because of poor selectivity. Given the roles of CDK2 in tumorigenesis, selective CDK2 inhibition may provide therapeutic benefits against certain cancer. In this study, a series of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives were designed, synthesized, and evaluated. The most selective compound DC-K2in212 in this series exhibited high potency towards CDK2 and had effective anti-proliferative activity against A2058 melanoma cell line and MV4-11 leukemia cell line while exhibiting low toxic effect on human normal cell lines MRC5 and LX2. The molecular modeling illustrated that compound DC-K2in212 had the similar binding mode with CDK2 as C-73, the most selective CDK2 inhibitor reported so far, which might account for selectivity against CDK2 over CDK1. Further biological studies revealed that compound DC-K2in212 suppressed CDK2-associated downstream signaling pathway, blocked cell cycle progression, and induced cellular apoptosis. Therefore, compound DC-K2in212 could serve as a potential CDK2 inhibitor for further development. (c) 2021 Elsevier Masson SAS. All rights reserved.

Name: 2,6-Difluorobenzoic acid. Bye, fridends, I hope you can learn more about C7H4F2O2, If you have any questions, you can browse other blog as well. See you lster.

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SDS of cas: 385-00-2. In 2020 MOLECULES published article about MOLECULAR-ORBITAL METHODS; CRYSTAL-STRUCTURES; CARBOXYLIC-ACIDS; GAS-PHASE; 2-FLUOROBENZOIC ACID; HIRSHFELD SURFACES; INFRARED-SPECTRA; ENERGY; PHOTOCHEMISTRY; DEGRADATION in [Ildiz, Gulce Ogruc; Fausto, Rui] Univ Coimbra, Dept Chem, CQC, P-3004535 Coimbra, Portugal; [Ildiz, Gulce Ogruc] Istanbul Kultur Univ, Fac Sci & Letters, Dept Phys, Atakoy Campus, TR-34156 Istanbul, Turkey in 2020, Cited 85. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2.

This article presents a detailed comprehensive investigation of the ortho fluoro- and chloro- substituted benzoic acids both, as isolated molecules and in the crystalline phase. Quantum chemical calculations performed within the density functional theory (DFT) formalism are used to investigate the potential energy landscapes of the molecules, taking into special consideration the effects of the interactions between the carboxylic group and the ortho halogen substituents, as well as the nature of these later on the structure and properties of the investigated systems. The structures of the relevant conformers of the molecules are discussed in comparative terms, and used to rationalize experimental data obtained for the compounds in the gas phase and isolated in low-temperature inert matrices. The UV-induced photofragmentation reactions of two of the compounds isolated in cryogenic inert matrices were studied as illustrative cases. The structures of the crystals reported previously in the literature are revisited and discussed also in a comparative basis. Particular emphasis is given to the analysis of the intermolecular interactions in the different crystals, using Hirshfeld surface analysis, the CE-B3LYP energy decomposition model and the HOMA index, and to their correlation with thermodynamic data.

SDS of cas: 385-00-2. Bye, fridends, I hope you can learn more about C7H4F2O2, If you have any questions, you can browse other blog as well. See you lster.

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An article Room temperature clickable coupling electron deficient amines with sterically hindered carboxylic acids for the construction of amides WOS:000597946100010 published article about CATIONIC-AMPHIPHILIC POLYMERS; PRIMARY ALCOHOLS; MEDICINAL CHEMISTS; DRUG DISCOVERY; BOND FORMATION; PEPTIDE; PHENOLS; REAGENTS; TRANSFORMATION; CONVERSION in [Liu, Jing; Qin, Hua-Li] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 205 Luoshi Rd, Wuhan 430070, Peoples R China; [Wang, Shi-Meng] Wuchang Univ Technol, Sch Life Sci, Wuhan 430223, Peoples R China in 2020, Cited 86. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2. COA of Formula: C7H4F2O2

A method for the synthesis of difficult-to-access amides was developed through the coupling of sterically hindered carboxylic acids and electron deficient amines via SO2F2-mediated dehydration. The method feathers with broad substrate scope, mild conditions, excellent functional group compatibility and high yields. (C) 2020 Elsevier Ltd. All rights reserved.

COA of Formula: C7H4F2O2. Bye, fridends, I hope you can learn more about C7H4F2O2, If you have any questions, you can browse other blog as well. See you lster.

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Zare, A; Dianat, M; Eskandari, MM in [Zare, Abdolkarim; Dianat, Manije] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran; [Eskandari, Mohammad Mehdi] RIPI, Nanotechnol Res Ctr, POB 1485733111, Tehran, Iran published A novel organic-inorganic hybrid material: production, characterization and catalytic performance for the reaction of arylaldehydes, dimedone and 6-amino-1,3-dimethyluracil in 2020.0, Cited 47.0. SDS of cas: 93-02-7. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

A novel silica-based organic-inorganic hybrid material namely N,N,N ‘,N ‘-tetramethyl-N-(silica-n-propyl)-N ‘-sulfonic acid-ethylenediaminium chloride/mesylate ([TSSECM]) was prepared, and characterized by EDS (energy-dispersive X-ray spectroscopy), FE-SEM (field emission scanning electron microscopy), FT-IR, XRD (X-ray diffraction), TGA (thermal gravimetric analysis) and adsorption/desorption porosimetry analyses. The sizes of most particles of [TSSECM] were less than 100 nm (i.e. they were nanomaterials), and some particles had sizes more than 100 nm (up to 185 nm). The hybrid material was applied as a highly efficacious, recyclable and dual-functional catalyst for the one-pot multi-component reaction of arylaldehydes, dimedone and 6-amino-1,3-dimethyluracil under solvent-free conditions to give pyrimido[4,5-b]quinolines.

SDS of cas: 93-02-7. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Zare, A; Dianat, M; Eskandari, MM or concate me.

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Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2021 ORG LETT published article about AROMATIC AMIDES; CATALYZED ALKYLATION; BONDS; DERIVATIVES in [Das, Amrita; Chatani, Naoto] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan in 2021, Cited 47. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2. Recommanded Product: 2,6-Difluorobenzoic acid

The Rh-catalyzed C-H alkylation of benzylamine derivatives with unactivated 1-alkenes that proceeds via a picolinamide directing group is reported. The crucial role of an acid additive in this transformation is confirmed. Aromatic acids showed high linear selectivity, and aliphatic acids provided branched alkylation products as the major product. The reaction has a broad scope for benzylamines and alkenes. Deuterium labeling experiments suggest that a Rh-carbene intermediate is involved in the case of linear product formation. A different reaction pathway, however, appears to be involved in the case of branched alkylation products, and this pathway also appeared to be a minor pathway in linear-selective reactions.

Recommanded Product: 2,6-Difluorobenzoic acid. About 2,6-Difluorobenzoic acid, If you have any questions, you can contact Das, A; Chatani, N or concate me.

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Isothiazole – Wikipedia,
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