Tag: M.W=150-200

Product Details of 93-02-7. Authors Swain, B; Abhay; Singh, P; Angeli, A; Aashritha, K; Nagesh, N; Supuran, CT; Arifuddin, M in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Swain, Baijayantimala; Abhay; Singh, Priti; Aashritha, Kamtam; Arifuddin, Mohammed] Natl Inst Pharmaceut Educ & Res NIPER, Dept Med Chem, Hyderabad 500037, India; [Angeli, Andrea; Supuran, Claudiu T.] Univ Firenze, Neurofarba Dept, Sez Sci Farmaceut & Nutraceut, Via Ugo Schiff 6, I-50019 Florence, Italy; [Arifuddin, Mohammed] Anwarul Uloom Coll, Dept Chem, 11-3-918 New Malleypally, Hyderabad 500001, India; [Nagesh, Narayana] Ctr Cellular & Mol Biol CCMB, Hyderabad, India in 2021, Cited 24. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7

A new series of benzenesulphonamide linked-1,3,4-oxadiazole hybrids (6a?s) has been synthesized and tested for their carbonic anhydrase inhibition against human (h) carbonic anhydrase (CA) isoforms hCA I, II, IX, and XIII. Fluorescence properties of some of the synthesized molecules were studied. Most of the molecules exhibited significant inhibitory power, comparable or better than the standard drug acetazolamide (AAZ) on hCA XIII. Out of 19 tested molecules, compound 6e (75.8 nM) was 3 times more potent than AAZ (250.0 nM) against hCA I, whereas compound 6e (15.4 nM), 6g (16.2 nM), 6h (16.4 nM) and 6i (17.0 nM) were found to be more potent than AAZ (17.0 nM) against isoform hCA XIII. It is anticipated that these compounds could be taken as the potential leads for the development of selective hCA XIII isoform inhibitors with improved potency.

Product Details of 93-02-7. Welcome to talk about 93-02-7, If you have any questions, you can contact Swain, B; Abhay; Singh, P; Angeli, A; Aashritha, K; Nagesh, N; Supuran, CT; Arifuddin, M or send Email.

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I found the field of Chemistry very interesting. Saw the article Synthesis of novel 8-nitro-substituted 1,3-benzothiazin-4-ones published in 2020. COA of Formula: C7H4F2O2, Reprint Addresses Nosova, EV (corresponding author), Ural Fed Univ, Inst Chem Engn, Ekaterinburg 620002, Russia.; Nosova, EV (corresponding author), Russian Acad Sci, I Ya Postovsky Inst Organ Synth, Ural Branch, Ekaterinburg 620990, Russia.. The CAS is 385-00-2. Through research, I have a further understanding and discovery of 2,6-Difluorobenzoic acid

New 2,5-bis(azacyclohex-1-yl)-8-nitro-1,3-benzothiazin-4-ones were synthesized from 2,6-difluorobenzoic acid in two preparative stages. The ethoxycarbonylpiperazino derivative surpasses in tuberculostatic activity (MIC 4 mu g ml(-1)) its 5-fluoro-8-H-counterpart. The first representative of 5-fluoro-8-nitro-1,3-benzothiazin-4-ones was obtained through the condensation of 2,6-difluoro-3-nitrobenzoyl isothiocyanate and N-methylindole.

About 2,6-Difluorobenzoic acid, If you have any questions, you can contact Nosova, EV; Batanova, OA; Lipunova, GN; Charushin, VN or concate me.. COA of Formula: C7H4F2O2

Reference:
Isothiazole – Wikipedia,
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Recently I am researching about 3-COMPONENT DOMINO REACTIONS; SOLVENT-FREE; REGIOSELECTIVE SYNTHESIS; RATIONAL DESIGN; GREEN SYNTHESIS; IONIC LIQUIDS; CATALYST; BIOASSAY; QSAR, Saw an article supported by the National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21571087]; Open Foundation of Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials [K201312]; Natural Science Foundation of the Jiangsu Higher Education Institutions of ChinaNational Natural Science Foundation of China (NSFC) [18KJA150004]; TAPP [PPZY2015B110]. Published in WILEY in HOBOKEN ,Authors: Pan, ZB; Xu, H; Mao, KM; Dai, L; Zhao, LM; Rong, LC. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde. Product Details of 93-02-7

In this research, we have developed an efficient three-component reaction for the synthesis of pyrano[3,2-c]pyridine derivatives from the reaction of aromatic aldehydes, tert-butyl 2,4-dioxopiperidine-1-carboxylate, and N-methyl-1-(methylthio)-2-nitroethylen-1-amine in [BMIM]BF4 medium. The advantages of this method were readily available starting materials, simple reaction conditions, and satisfactory yields.

Product Details of 93-02-7. Welcome to talk about 93-02-7, If you have any questions, you can contact Pan, ZB; Xu, H; Mao, KM; Dai, L; Zhao, LM; Rong, LC or send Email.

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An article Gold Catalyzed Decarboxylative Cross-Coupling of Iodoarenes WOS:000557854400036 published article about VISIBLE-LIGHT PHOTOREDOX; OXIDATIVE ADDITION; LIGAND DESIGN; ARYL HALIDES; COMPLEXES; REACTIVITY; ACTIVATION; PALLADIUM; PROTODEBORONATION; ARENES in [Daley, Ryan A.; Topczewski, Joseph J.] Univ Minnesota Twin Cities, Dept Chem, Minneapolis, MN 55455 USA; [Morrenzin, Aaron S.; Neufeldt, Sharon R.] Montana State Univ, Dept Chem & Biochem, Bozeman, MT 59717 USA in 2020, Cited 92. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2. Category: isothiazole

This report details a decarboxylative cross-coupling of (hetero)aryl carboxylates with iodoarenes in the presence of a gold catalyst (>25 examples, up to 96% yield). This reaction is site specific, which overcomes prior limitations associated with gold catalyzed oxidative coupling reactions. The reactivity of the (hetero)aryl carboxylate correlates qualitatively to the field effect parameter (F-ortho). Reactions with isolated gold complexes and DFT calculations support a mechanism proceeding through oxidative addition at a gold(I) cation with decarboxylation being viable at either a gold(I) or a silver(I) species.

Welcome to talk about 385-00-2, If you have any questions, you can contact Daley, RA; Morrenzin, AS; Neufeldt, SR; Topczewski, JJ or send Email.. Category: isothiazole

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In 2020 MOLECULES published article about MOLECULAR-ORBITAL METHODS; CRYSTAL-STRUCTURES; CARBOXYLIC-ACIDS; GAS-PHASE; 2-FLUOROBENZOIC ACID; HIRSHFELD SURFACES; INFRARED-SPECTRA; ENERGY; PHOTOCHEMISTRY; DEGRADATION in [Ildiz, Gulce Ogruc; Fausto, Rui] Univ Coimbra, Dept Chem, CQC, P-3004535 Coimbra, Portugal; [Ildiz, Gulce Ogruc] Istanbul Kultur Univ, Fac Sci & Letters, Dept Phys, Atakoy Campus, TR-34156 Istanbul, Turkey in 2020, Cited 85. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2. Product Details of 385-00-2

This article presents a detailed comprehensive investigation of the ortho fluoro- and chloro- substituted benzoic acids both, as isolated molecules and in the crystalline phase. Quantum chemical calculations performed within the density functional theory (DFT) formalism are used to investigate the potential energy landscapes of the molecules, taking into special consideration the effects of the interactions between the carboxylic group and the ortho halogen substituents, as well as the nature of these later on the structure and properties of the investigated systems. The structures of the relevant conformers of the molecules are discussed in comparative terms, and used to rationalize experimental data obtained for the compounds in the gas phase and isolated in low-temperature inert matrices. The UV-induced photofragmentation reactions of two of the compounds isolated in cryogenic inert matrices were studied as illustrative cases. The structures of the crystals reported previously in the literature are revisited and discussed also in a comparative basis. Particular emphasis is given to the analysis of the intermolecular interactions in the different crystals, using Hirshfeld surface analysis, the CE-B3LYP energy decomposition model and the HOMA index, and to their correlation with thermodynamic data.

Product Details of 385-00-2. Welcome to talk about 385-00-2, If you have any questions, you can contact Ildiz, GO; Fausto, R or send Email.

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Isothiazole – Wikipedia,
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An article Machine learning-based prediction of toxicity of organic compounds towards fathead minnow WOS:000574586100059 published article about QSAR MODEL; DESCRIPTORS; MOLECULES; CHEMICALS in [Chen, Xingmei; Dang, Limin; Yang, Hai; Huang, Xianwei; Yu, Xinliang] Hunan Inst Engn, Coll Mat & Chem Engn, Hunan Prov Key Lab Environm Catalysis & Waste Reg, Xiangtan 411104, Hunan, Peoples R China; [Yu, Xinliang] Donghu Rd 18, Xiangtan 411104, Hunan, Peoples R China in 2020, Cited 30. Computed Properties of C7H4F2O2. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2

Predicting the acute toxicity of a large dataset of diverse chemicals against fathead minnows (Pimephales promelas) is challenging. In this paper, 963 organic compounds with acute toxicity towards fathead minnows were split into a training set (482 compounds) and a test set (481 compounds) with an approximate ratio of 1 : 1. Only six molecular descriptors were used to establish the quantitative structure-activity/toxicity relationship (QSAR/QSTR) model for 96 hourpLC(50)through a support vector machine (SVM) along with genetic algorithm. The optimal SVM model (R-2= 0.756) was verified using both internal (leave-one-out cross-validation) and external validations. The validation results (q(int)(2)= 0.699 andq(ext)(2)= 0.744) were satisfactory in predicting acute toxicity in fathead minnows compared with other models reported in the literature, although our SVM model has only six molecular descriptors and a large data set for the test set consisting of 481 compounds.

Welcome to talk about 385-00-2, If you have any questions, you can contact Chen, XM; Dang, LM; Yang, H; Huang, XW; Yu, XL or send Email.. Computed Properties of C7H4F2O2

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I found the field of Chemistry very interesting. Saw the article Total Synthesis of Naphterpin and Marinone Natural Products published in 2019.0. Product Details of 93-02-7, Reprint Addresses George, JH (corresponding author), Univ Adelaide, Dept Chem, Adelaide, SA 5005, Australia.. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde

A concise and divergent strategy for the synthesis of the naphterpin and marinone meroterpenoid families has been developed. The approach features a succession of pericyclic reactions-an aromatic Claisen rearrangement, a retro-6 pi-electrocyclization, and two Diels-Alder reactions-which facilitated the first total synthesis of naphterpin itself in five steps from 2,5-dimethoxyphenol, alongside similar syntheses of 7-demethylnaphterpin and debromomarinone. Late-stage oxidation and bromination reactions were also investigated, leading to the first total syntheses of naphterpins B and C and isomarinone.

Product Details of 93-02-7. Welcome to talk about 93-02-7, If you have any questions, you can contact Murray, LAM; Fallon, T; Sumby, CJ; George, JH or send Email.

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Name: 2,6-Difluorobenzoic acid. In 2020 MOLECULES published article about MOLECULAR-ORBITAL METHODS; CRYSTAL-STRUCTURES; CARBOXYLIC-ACIDS; GAS-PHASE; 2-FLUOROBENZOIC ACID; HIRSHFELD SURFACES; INFRARED-SPECTRA; ENERGY; PHOTOCHEMISTRY; DEGRADATION in [Ildiz, Gulce Ogruc; Fausto, Rui] Univ Coimbra, Dept Chem, CQC, P-3004535 Coimbra, Portugal; [Ildiz, Gulce Ogruc] Istanbul Kultur Univ, Fac Sci & Letters, Dept Phys, Atakoy Campus, TR-34156 Istanbul, Turkey in 2020, Cited 85. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2.

This article presents a detailed comprehensive investigation of the ortho fluoro- and chloro- substituted benzoic acids both, as isolated molecules and in the crystalline phase. Quantum chemical calculations performed within the density functional theory (DFT) formalism are used to investigate the potential energy landscapes of the molecules, taking into special consideration the effects of the interactions between the carboxylic group and the ortho halogen substituents, as well as the nature of these later on the structure and properties of the investigated systems. The structures of the relevant conformers of the molecules are discussed in comparative terms, and used to rationalize experimental data obtained for the compounds in the gas phase and isolated in low-temperature inert matrices. The UV-induced photofragmentation reactions of two of the compounds isolated in cryogenic inert matrices were studied as illustrative cases. The structures of the crystals reported previously in the literature are revisited and discussed also in a comparative basis. Particular emphasis is given to the analysis of the intermolecular interactions in the different crystals, using Hirshfeld surface analysis, the CE-B3LYP energy decomposition model and the HOMA index, and to their correlation with thermodynamic data.

Welcome to talk about 385-00-2, If you have any questions, you can contact Ildiz, GO; Fausto, R or send Email.. Name: 2,6-Difluorobenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2021.0 RSC ADV published article about ONE-POT SYNTHESIS; FE3O4 NANOPARTICLES; REUSABLE CATALYST; HIGHLY EFFICIENT; BIFUNCTIONAL NANOCATALYST; MULTICOMPONENT SYNTHESIS; HETEROGENEOUS CATALYST; SAPONINS; NANOCOMPOSITE; ALKALOIDS in [Kazemnejadi, Milad; Nasseri, Mohammad Ali; Sheikh, Safoora; Rezazadeh, Zinat; Gol, Seyyedeh Ameneh Alavi] Univ Birjand, Fac Sci, Dept Chem, POB 97175-615, Birjand, Iran; [Sheikh, Safoora] Univ Regensburg, Inst Organ Chem, Univ Str 31, D-93053 Regensburg, Germany in 2021.0, Cited 76.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7. Formula: C9H10O3

Saponin, as a green and available phytochemical, was immobilized on the surface of magnetite nanoparticles then doped with Cu ions (Fe3O4@Sap/Cu(ii)) and used as an efficient nanocatalyst for the synthesis of quinazoline and acridine derivatives, due to their high application and importance in various fields of science. Different spectroscopic and microscopic techniques were used for the catalyst characterization such as FT-IR, XRD, FE-SEM, EDX, TEM, TGA, VSM, BET, DLS, CV, and XPS analyses. All characterization data were correlated with each other so that the structure of the catalyst was accurately characterized. The reactions were performed in the presence of a low amount of Fe3O4@Sap/Cu(ii) (0.42 mol%) as a green catalyst in water over a short period of time. The results show well the effective role of saponin in solving the problem of mass transfer in aqueous medium, which is the challenge of many organic reactions in aqueous medium and in the presence of heterogeneous medium. High catalytic activity was found for the catalyst and high to excellent efficiency was obtained for all quinazoline (68-94% yield) and acridine (66-97% yield) derivatives in short reaction times (less than 1 hour) under mild reaction conditions in the absence of any hazardous or expensive materials. There is not any noticeable by-product found whether for acridine or quinazoline derivatives, which reflects the high selectivity. Two reasonable mechanisms were proposed for the reactions based on observations from control experiments as well as literature reports. The catalyst could be easily recovered magnetically for at least six consecutive runs with insignificant reactivity loss.

Formula: C9H10O3. Welcome to talk about 93-02-7, If you have any questions, you can contact Kazemnejadi, M; Nasseri, MA; Sheikh, S; Rezazadeh, Z; Gol, SAA or send Email.

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Quality Control of 2,5-Dimethoxybenzaldehyde. In 2021 SILICON-NETH published article about ONE-POT SYNTHESIS; 3-COMPONENT SYNTHESIS; GREEN SYNTHESIS; AQUEOUS-MEDIA; 3-METHYL-4-ARYLMETHYLENE-ISOXAZOL-5(4H)-ONES; DERIVATIVES; ZEOLITES; FACILE; ISOXAZOLE-5(4H)-ONES; NANOCATALYST in [Kalhor, Mehdi; Samiei, Sima; Mirshokraie, Seyed Ahmad] Univ Payame Noor, Dept Chem, POB 19395-4697, Tehran, Iran in 2021, Cited 59. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

In this project, nano-MnO2@zeolite-Y (NMOZ) was successfully prepared via hydrothermal technique and its structure was confirmed using FT-IR, XRD, FE-SEM, EDX and BET analyses. MnO2 nanoparticles stabilized on zeolite-NaY were used as nanocatalyst for efficient solventless preparation of 3,4-disubstituted isoxazole-5(4H)-one scaffolds via one-pot three-component reaction of ethyl acetoacetate, hydroxylamine hydrochloride, and aromatic aldehydes at 100 degrees C. One of the advantages of this new method is the non-use of a metal oxidant such as KMnO4 (greener method) and the stabilization of MnO2 to the zeolite-Y surface via ion bonding. This causes the MnO2 not be leached from the zeolite during the processes of nanocatalyst recycling in organic reactions. This simple approach also has promising features as like as safe, inexpensive and recyclable nanocatalyst, solvent-free reaction, short reaction times, high to excellent yields, and easy isolation of the products.

Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 2,5-Dimethoxybenzaldehyde

Reference:
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