It is a common heterocyclic compound, the isothiazole compound, 3-Chlorobenzo[d]isothiazole, cas is 7716-66-7 its synthesis route is as follows.,7716-66-7
10.2 grams of piperidine,Mix 4.0 g of 3-chloro-1,2-benzothiazole and 10 ml of ethanol and mix at 80 ¡ã C under refluxAfter 18 hours, it was cooled, poured into water, separated with 100 ml of water and 200 ml of toluene, and the organic phase was washed with 100 ml of water. Dry, filter, concentrate to 20 ml, and refrigerate overnight (0-5 ¡ã C) in the refrigerator. Precipitation appeared, filtered to give a white solid, yield79.6percent.
With the complex challenges of chemical substances, we look forward to future research findings about 3-Chlorobenzo[d]isothiazole
Reference£º
Patent; Capital University of Medical Sciences; Jin Zengliang; Gao Nana; Zheng Yuanyuan; Xu Huanli; Li Xiaorong; Xiong Jie; (20 pag.)CN108440520; (2018); A;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com