Application of 288-16-4, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Application of 288-16-4, Name is Isothiazole, molecular formula is C3H3NS. In a Article, authors is Revesz, Laszlo£¬once mentioned of Application of 288-16-4
SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38 MAP kinase inhibitors
2,6-Diamino-3,5-difluoropyridinyl substituted pyridinylimidazoles, -pyrroles, -oxazoles, -thiazoles and -triazoles have been identified as novel p38alpha inhibitors. Pyridinylimidazole 11 potently inhibited LPS-induced TNFalpha in mice, showed good efficacy in the established rat adjuvant (ED50: 10 mg/kg po b.i.d.) and collagen induced arthritis (ED50: 5 mg/kg po b.i.d.) with disease modifying properties based on histological analysis of the joints.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 288-16-4 is helpful to your research. Application of 288-16-4
Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com